La&bacillus (Thermobacterium) acidophilus R-26 has a specific requirement for a preformed deoxyribonucleoside residue. Oligodeoxyribonucleotides and 5’-deoxyribonucleotides are active. However, this requirement is not replaced by vitamin Blz (1, 2). Previous nutritional studies have shown that ribonucleotides inhibit the deoxyribonucleoside activity’ of 5’-deoxyribonucleotides for L. acidophili...

Sulfobacillus acidophilus TPY, isolated from a hydrothermal vent in the Pacific Ocean, is a moderately thermoacidophilic Gram-positive bacterium that can oxidize ferrous iron or sulfur compounds to obtain energy. In this study, comparative transcriptomic analyses of S. acidophilus TPY were performed under different redox conditions. Based on these results, pathways involved in sulfur metabolism...

this study investigated the survival of a probiotic strain of lactobacillus acidophilus (la-5) in jug cheese during storage (120 days at 6-8 °c). the jug cheese treatments were: c (control), containing commercial starter frc-65; la, containing lactobacillus acidophilus; and las, containing commercial starter and lactobacillus acidophilus. the results showed that the amount of lactobacillus acid...

OBJECTIVE To isolate bacteriocin from a vaginal strain of Lactobacillus acidophilus. METHODS L. acidophilus 160 was grown on two media. The first was MRS broth for 18 hours; the cells were harvested, washed, and placed into a chemically defined medium. The second medium resembled vaginal fluid minus protein. Bacteriocin was precipitated from both media using ammonium sulfate. The growth-inhib...

Small heat shock proteins (sHsps) are ubiquitous conserved chaperone-like proteins involved in cellular proteins protection under stressful conditions. In this study, a reverse transcription quantitative PCR (RT-qPCR) procedure was developed and used to quantify the transcript level of a small heat shock gene (shs) in the probiotic bacterium Lactobacillus acidophilus NCFM, under stress conditio...

Lactobacillus acidophilus 30SC has been isolated from swine intestines and considered a probiotic strain for dairy products because of its ability to assimilate cholesterol and produce bacteriocins. Here, we report the complete genome sequence of Lactobacillus acidophilus 30SC (2,078,001 bp) exhibiting strong acid resistance and enhanced bile tolerance.

Many foods and food components boost the immune system, but little data are available regarding the mechanisms by which they do. Bacterial strains have disparate effects in stimulating the immune system. In dendritic cells, the gram-negative bacteria Escherichia coli upregulates proinflammatory cytokines, whereas gram-positive Lactobacillus acidophilus induces a robust interferon (IFN)-β respon...

At the 1920 meeting of the Society of American Bacteriologists a paper, published only in abstract form (Sherman, 1921), presented some characteristics of Lactobacillus bulgaricus, differentiating this organism from certain other lactobacilli. Eighteen cultures of Lactobacillus bulgaricus were then studied; a number of Lactobacillus casei; a few cultures from feces, assumed to belong to the Lac...

The objective of this study is to determine the viability of Lactobacillus acidophilus NCFM and Lactobacillus rhamnosus HN001 in Edam cheese as well as the effect of probiotic bacteria on paracasein proteolysis and changes in the water activity during ripening. The use of probiotics L. rhamnosus HN001 and L. acidophilus NCFM in Edam cheese slightly changed its chemical composition, but the chan...

Two commercially available isolates of Lactobacillus acidophilus (NCFM and LA-1) were compared for their capacities to protect immunodeficient bg/bg-nu/un and bg/bg-nu/+ mice from candidiasis. L. acidophilus NCFM prolonged survival of adult and neonatal bg/bg-nu/nu mice, inhibited disseminated candidiasis in both mouse strains, suppressed weight loss associated with Candida albicans infection i...