The structure of bovine heart mitochondrial NADH dehydrogenase was investigated by cross-linking constituent subunits with disuccinimidyl tartrate, (ethylene glycol)yl bis(succinimidyl succinate) and dimethyl suberimidate. Cross-linked products were identified by Western blotting with monospecific antisera to nine subunits of the enzyme. Cross-links between subunits within the flavoprotein, iro...

The knowledge of biological trace minerals and phytase requirements for modern broiler genotypes is not established the pressure to reduce their usage in animal feeding due environmental issues increasing. Here, alkaline phosphatase (ALP) tartarate-resistant acid (TRAP) tibia serum broilers fed with diets containing various levels reduced zinc, manganese, copper was evaluated. experiment perfor...

The interactions between Factor B (B), its activation products Ba and Bb, properdin (P) and C3i or C3b, components that together form the alternative-pathway C3 convertase enzyme of human complement, have been analysed. Fluid-phase complexes of the purified components C3i, B and P were probed with the homobifunctional cross-linking reagent disuccinimidyl tartarate, and efficient cross-linking o...

An 80 year old female in good general health was diagnosed with normal tension glaucoma and was prescribed Alphagant (brimonidine tartarate 0.2%) twice daily in both eyes. The intraocular pressure decreased from 15 mmHg to 11 mmHg bilaterally. The patient did not complain of any side effects when using the brimonidine drops. Exactly one year later, she presented with a sudden onset of chemosis,...

the objective of present research was to design, evaluate and compare drug release from two different dosage forms in pulsatile drug delivery system (dds) for metoprolol tartarate (mt) as tablet and capsule. pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal delivery ...

Background : Bone resorption can be assessed by measuring plasma tartarate resistant acid phosphatase and urinary excretion of collagen degradation products: Hydroxyproline,Hydroxylysine glycosides,pyridinium crosslinks and associated peptides. We compared the excretion of Hydroxyproline in women of premenopausal age group to those of post menopausal age group and found a significant difference...

AIMS Omentin-1 (also known as intelectin-1) is a recently identified visceral adipose tissue-derived cytokine that is inversely related to obesity. Our previous study showed that omentin-1 inhibits osteoblastic differentiation of calcifying vascular smooth muscle cells (CVSMCs) in vitro. This study was undertaken to investigate the effects of omentin-1 on arterial calcification and bone metabol...