I . The distribution of copper, zinc and manganese in seven regions of the brain, liver, heart, muscle from the abdominal wall, and skin of children was determined by means of atomic absorption spectrophotometry. 2. The results showed significantly lower levels of Cu, Zn and Mn in livers of children with kwashiorkor compared with control subjects. The concentrations of these three elements were...

Redmond, A. 0. B., Kaschula, R. 0. C., Freeseman, C., and Hansen, J. D. L. (1971). Archives of Disease in Childhood, 46, 470. The colon in kwashiorkor. The colon in kwashiorkor was investigated by means of rectal biopsy and sigmoidoscopy in 20 children, followed by barium enema in 10 of the children. The colon during the acute phase of the disease showed a surface epithelial atrophy, with infil...

A hospital-based case control study was carried out to determine the pattern of infections and immunoblobulin levels in Sudanese children with severe protein energy malnutrition (PEM). The pre-dietary rehabilitation levels of the three major immunoglobulins (IgG, IgA and IgM) were compared with those of normal controls, and with the levels after dietary rehabilitation. Eighty one children were ...

Children with kwashiorkor almost invariably have diarrhoea which may be severe and prolonged. The exact cause is often obscure and the management unsatisfactory (Brock et al., 1955; Trowell, 1958; Pretorius and Smit, 1958). Recently Bowie, Brinkman, and Hansen (1965), and Bowie, Barbezat, and Hansen (1967) found that the majority of their kwashiorkor patients with severe diarrhoea responded wit...

The work chosen as this month’s public health classic and reproduced on the following pages is one of the most widely cited papers on childhood malnutrition: in 1935, Cicely D. Williams introduced the West African name kwashiorkor into the scientific literature of nutritional diseases (1). Williams identified the condition as being associated with the social situation of the affected child in t...