Scurvy is associated with abnormal carbohydrate metabolism and diminished production of insulin (1). Banerjee et al. (2) observed increased accumulation of citrate, malate, and lactate in the tissues of scorbutic guinea pigs. This was possibly due to the insulin insufficiency associated with scurvy since prolonged injection of insulin to scorbutic guinea pigs diminished the tissue concentration...

Scurvy is associated with abnormal carbohydrate metabolism and diminished production of insulin (1). Banerjee et al. (2) observed increased accumulation of citrate, malate, and lactate in the tissues of scorbutic guinea pigs. This was possibly due to the insulin insufficiency associated with scurvy since prolonged injection of insulin to scorbutic guinea pigs diminished the tissue concentration...

The oxidation of glutamic acid by avirulent strains of Brucella abortus is the most rapid respiratory process thus far studied in this species (Gerhardt et al., 1950a). Furthermore, glutamic acid will serve as the sole source of both carbon and nitrogen for all strains of B. abortus which have been tested (Gerhardt et al., 1950b). Glutamic acid is important in the synthesis of other amino acids...

Homoaconitic acid, the second intermediate of the proposed pathway for lysine biosynthesis in yeast, is accumulated in the growth medium of a lysine-requiring mutant. This acid has been identified on paper and column chromatography by comparing it with authentic cis-homoaconitic acid. The infrared spectrum of the isolated material was identical with that of synthetic cis-homoaconitic acid. In a...

Abstract Polycarboxylic acids (PACs) are important metabolic products in almost all living bodies, yet current analytical methods for detection of PACs tea beverages still unsatisfactory due to the complex matrix and physicochemical properties PACs. In this work, a rapid method was developed simultaneous determination 7 PACs, including tartaric acid, α-ketoglutaric malic malonic cis-aconitic su...