The objective of this study was to determine whether the permeability characteristics of the nuclear envelope vary during different phases of cellular activity. Both passive diffusion and signal-mediated transport across the envelope were analyzed during the HeLa cell cycle, and also in dividing, confluent (growth-arrested), and differentiated 3T3-LI cultures. Colloidal gold stabilized with BSA...

•Double networks with a synergy effect are designed for high-performance thermocells•Stretchable thermocells show extraordinary toughness even higher than cartilages•Robust capable of loading high concentrations electrolytes•The thermocell reaches the highest-level power density in quasi-solid Thermocells have recently attracted increasing interest field Internet Things owing to their capacity ...

Storage of photovoltaic and wind electricity in batteries could solve the mismatch problem between the intermittent supply of these renewable resources and variable demand. Flow batteries permit more economical long-duration discharge than solid-electrode batteries by using liquid electrolytes stored outside of the battery. We report an alkaline flow battery based on redox-active organic molecu...

One strategy used for gene therapy of cancer is molecular chemotherapy. This approach is based on selective expression of an encoded toxin in cancer cells to achieve their eradication. One potential advantage of this strategy derives from a phenomenon, termed the bystander effect, whereby only a fraction ofcells needs to be transduced to eradicate a tumor population. Despite the theoretical adv...

One of the best understood signal transduction pathways activated by receptors containing seven transmembrane domains involves activation of heterotrimeric G-protein complexes containing Gs , the subsequent stimulation of adenylyl cyclase, production of cAMP, activation of protein kinase A (PKA), and the phosphorylation of substrates that control a wide variety of cellular responses. Here, we r...

Nonaqueous potassium-ion batteries have emerged as possible lowcost alternatives to Li-ion batteries for large-scale energy storage, owing to their ability to use graphitic carbon as the negative electrode. Positive electrode materials remain a challenge. Here, we report control of the crystal dimensions of the Prussian white hexacyanoferrate (HCF), K1.7Fe[Fe(CN)6]0.9, using solution chemistry ...

Ocean Drilling Program (ODP) Leg 199, “The Paleogene Equatorial Transect” (Sites 1215 through 1222), was designed to study the evolution of the equatorial Pacific current and wind system as the Earth went from maximum Cenozoic warmth to initial Antarctic glaciations. The drilling program was primarily devoted to a transect along 56to 57-Ma crust, old enough to capture the Paleocene/ Eocene boun...