Nature of Work: Japanese beetles (JB), Popillia japonica Newman, are destructive, highly polyphagus herbivores that show a general preference for plants in the Rosaceae family. Although Malus taxa are often found to be susceptible to JB, there are substantial differences in resistance among Malus species and cultivars (1,2). In a prior study, total phenolic levels in Malus were not correlated w...

Deoxycholic acid (DCA) has been implicated in colorectal carcinogenesis in humans with effects on proliferation and apoptosis, mediated at least in part by activation of transcription factors nuclear factor kappa B (NF-jB), activator protein 1 (AP-1) and protein kinase C (PKC) enzymes. Ursodeoxycholic acid (UDCA) is reported to reduce the frequency of colonic carcinogenesis in ulcerative coliti...

on pial arteriolar caliber, local cerebral blood flow, and the blood-brain barrier. Circ Res 39: 33-41, 1976 4. Brierley JB, Brown AW, MeMrum BS: The nature and time course of the neuronal alterations resulting from oligaemia and hypoglycaemia in the brain of Macaca mulatta. Brain Res 25: 483-499, 1971 5. Brown AW, Brierley JB: The nature, distribution and earliest stages of anoxic-ischaemic ne...

IjB proteins are known as the regulators of NF-jB activity. They bind tightly to NF-jB dimers, until stimulus-responsive N-terminal phosphorylation by IKK triggers their ubiquitination and proteasomal degradation. It is known that IjBa is an unstable protein whose rapid degradation is slowed upon binding to NF-jB, but it is not known what dynamic mechanisms control the steady-state level of tot...

In this article, we study geometric unitaries of JB-algebras (in particular, self-adjoint parts of C∗-algebras). We will show that the geometric unitaries of a JB algebra are precisely those central algebraic unitaries (or central symmetries). We will also show that the group of surjective isometries on a JB-algebra A (with point-norm topology) is the semi-direct product of the canonical action...

INTRODUCTION Amnesia or loss of memory is the cardinal hallmark of Alzheimer's disease (AD), a progressive neurodegenerative disorder associated with ageing process. Although, AD had been discovered over a century ago, drugs which could cure or halt the progression of the disease are yet to see the light of the day. However, there has been a growing interest in the use of phytomedicines with mu...