S elf reliance is not enough. Some organs rely on the kindness of others to control their size, according to Correct organ size is measured in mass, not cell numbers— forcing or blocking cell division generally does not change an organ's overall dimensions. Parker found the same is true in the fl y embryonic P compartment, which forms part of the larval epidermis. Increases in P compartment cel...

Angio eccrine hamartoma (EAH) is a rare, benign tumoral lesion composed of glands and vascular structures in the mid dermis. We report on two observations Dakar. Observation 1: A four-month-old infant was seen for an erythematous plaque, rounded, with smooth surface, asymptomatic, localized to right thigh, evolving three months. The clinical appearance suggested spitz tumour. Cutaneous histolog...

In real-world extraction of signal from data we are not given the needed signal prediction-error filter (PEF). Claerbout has taken S, the PEF of the signal, to be that of the data, S ≈ D. Spitz takes it to be S ≈ D/N . Where noises are highly predictable in time or space, Spitz gets significantly better results. Theoretically, a reason is that the essential character of a PEF is contained where...

BACKGROUND Spitz/Reed nevi are melanocytic lesions that may mimic melanoma at clinical, dermatoscopic and histopathological levels. Management strategies of these lesions remain controversial. OBJECTIVES We aim a correlation among clinical-dermatoscopic and histological features of a series of Spitz/Reed nevi diagnosed during 7 years at the Department of Dermatology. METHODS Clinical, derma...

OBJECTIVE To report the clinical evolution and handling of a Spitz nevus, from its initial flat feature to becoming an irregular, nodular, reddish lesion. CASE DESCRIPTION Female child, phototype II, with a small congenital nevus on the left lower limb and other sustained small nevi. The patient went through annual clinical and dermoscopic evaluations between the ages of three and seven, peri...

Neuroepithelial cell proliferation must be carefully balanced with the transition to neuroblast (neural stem cell) to control neurogenesis. Here, we show that loss of the Drosophila microRNA mir-8 (the homolog of vertebrate miR-200 family) results in both excess proliferation and ectopic neuroblast transition. Unexpectedly, mir-8 is expressed in a subpopulation of optic-lobe-associated cortex g...