Background:-Numerous attempts have been made in the past to attenuate haemodynamic responses occurring during laparoscopic cholecystectomy. The present study compared effect of three opioids namely TRAMADOL, Fentanyl and Nalbuphine obtundation cholecystectomy terms Heart rate, BP (SBP, DBP MAP) secondary aim was calculate duration analgesia sedation score. Materials And Methods:-This a randomis...

Opioid rotation has been proposed for management of cancer pain. No studies directly investigating dose equivalence between morphine injection (continuous IV administration) and the transdermal fentanyl patch have been reported. Therefore, we examined dose conversion ratios in patients undergoing opioid rotation from morphine injection to fentanyl patches. The subjects consisted of 45 patients ...

BACKGROUND Gabapentinoids have been used as preemptive analgesics for pain management following laparoscopic cholecystectomy. Recently, multimodal analgesic techniques have been found superior to preemptive analgesia alone. AIM The aim of this study is to evaluate and compare a single preoperative dose of pregabalin 150 mg and gabapentin 300 mg for pain relief following laparoscopic cholecyst...

Background & Aim: Although most patients experience severe pain after major spinal fixation surgery, little attention has been paid to control it with a multi-modal approach. The aim of this study is to select appropriate method of pain management after spinal surgery. Methods & Materials/Patients: This study was a randomized clinically controlled trial in candidates of spondylolisthesis and...

background & aim: although most patients experience severe pain after major spinal fixation surgery, little attention has been paid to control it with a multi-modal approach. the aim of this study is to select appropriate method of pain management after spinal surgery. methods & materials/patients: this study was a randomized clinically controlled trial in candidates of spondylolisthesis and sp...

Background Endotracheal intubation is an essential part of safe airway management but this stimulates the patient’s airway reflexes and predictably leads to haemodynamic derangement. Many drugs have been suggested in modifying in haemodynamic responses to laryngoscopy and intubation. Objectives To assess efficacy of three drugs esmolol, fentanyl and lignocaine and to assess which one is more ef...

BACKGROUND The objective of this study was to evaluate and compare the effects of three methods of using intravenous (IV), subcutaneous and intranasal (IN) fentanyl for pain management following general anesthesia in patients undergoing cesarean section. MATERIALS AND METHODS A prospective, randomized, single-blind clinical trial was done on 75 patients aged 20-40 years, American Society of A...

Background: Laparoscopic surgeries are commonly done in patients suffering from cholelithiasis. However, laparoscopic surgeries are associated with pneumoperitoneum, increased intra-abdominal pressure and insufflation of carbon dioxide leading to altered haemodynamic stability. We conducted a prospective randomised study to evaluate the effects of Clonidine and fentanyl in premedication for int...

PURPOSE This analysis was done to investigate the optimal regimen for fentanyl-based intravenous patient-controlled analgesia (IV-PCA) by finding a safe and effective background infusion rate and assessing the effect of adding adjuvant drugs to the PCA regimen. MATERIALS AND METHODS Background infusion rate of fentanyl, type of adjuvant analgesic and/or antiemetic that was added to the IV-PCA...

This prospective study was conducted to determine the sedative effects of IV ketamine and fentanyl on vital signs and behavior. Twenty-seven children, classified as ASA I, with a mean age of 34 months, were studied. The dosages of IV ketamine and fentanyl given were 0.5 mg/kg and 0.5 mcg/kg, respectively, approximately every 15-20 min. The pulse rate averaged 125 throughout the case. Blood pres...