Global Positioning System (GPS) and Inertial Navigation Systems (INS) are used for positioning and attitude determination in a wide range of applications. Since the usage of high performance INS is limited by its high cost, for general application areas low-cost INS units are used. Over the last few years, a number of low-cost inertial sensors have become available. However, these low cost sens...

Highlights An integrated GPS/INS/VNS navigation system was developed to improve accuracy. adaptive federal Kalman filter with information distribution factors used fuse information. Detection of seedling row lines achieved based on subregional feature points clustering. A modified rice transplanter as an experimental platform for automatic navigation. Abstract . In this article, global position...

The aim of the study is to design octaarginine (R8)-modified insulin-alginate nanoparticles (INS-SA/R8 NPs) as oral insulin delivery system, and further investigate its penetrating mechanism. characterization results indicated that surface INS-SA/R8 NPs was smooth average diameter about 300 nm. exhibited a stronger stability in simulated gastrointestinal fluids had better controlled release tha...

Regulation of Cl(-) channel conductance by Ins(3,4,5,6)P(4) provides receptor-dependent control over salt and fluid secretion, cell volume homeostasis, and electrical excitability of neurones and smooth muscle. Ignorance of how Ins(3,4,5,6)P(4) is synthesized has long hindered our understanding of this signaling pathway. We now show Ins(3,4,5,6)P(4) synthesis by Ins(1,3,4,5,6)P(5) 1-phosphatase...

Mutations in the insulin (INS) gene may cause permanent neonatal diabetes mellitus (PNDM). Ins2 mutant mouse models provided important insights into the disease mechanisms of PNDM but have limitations for translational research. To establish a large animal model of PNDM, we generated INS transgenic pigs. A line expressing high levels of INS mRNA (70–86% of wild-type INS transcripts) exhibited e...

Mutations in the insulin (INS) gene may cause permanent neonatal diabetes mellitus (PNDM). Ins2 mutant mouse models provided important insights into the disease mechanisms of PNDM but have limitations for translational research. To establish a large animal model of PNDM, we generated INS(C94Y) transgenic pigs. A line expressing high levels of INS(C94Y) mRNA (70-86% of wild-type INS transcripts)...

A new concept regarding to the GPS/INS integration, based on artificial intelligence here is presented. Most integrated inertial navigation systems (INS) and global positioning systems (GPS) have been implemented using the Kalman filtering technique with its drawbacks related to the need for predefined INS error model and observability of at least four satellites. Most recently, an INS/GPS inte...

The small scaffold protein PED/PEA-15 is involved in several different physiologic and pathologic processes, such as cell proliferation and survival, diabetes and cancer. PED/PEA-15 exerts an anti-apoptotic function due to its ability to interfere with both extrinsic and intrinsic apoptotic pathways in different cell types. Recent evidence shows that mice overexpressing PED/PEA-15 present large...

NIH 3T3 fibroblasts were stably transfected with rat brain inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) 3-kinase to explore the relationship between increased production of Ins(1,3,4,5)P4 and the formation of InsP5 and InsP6. Mass measurements of InsP5 and InsP6 revealed no significant difference between kinase- and vector-transfected fibroblasts. However, such 3-kinase-transfected cells, when l...

Autonomous underwater vehicles (AUV) are commonly used in many applications. Recently, the usage of multi-rotor unmanned autonomous (UAV) for marine applications is receiving more attention literature. Usually, both platforms employ an inertial navigation system (INS), and aiding sensors accurate solution. In AUV navigation, Doppler velocity log (DVL) mainly to aid INS, while UAVs, it common us...