Larix gmelinii, Pinaceae, Flavonoids, High-Performance Liquid Chromatography From needles of Larix gmelinii sixteen flavonoids were isolated and identified. The main flavonoids had been analyzed before, eight minor ones were identified as quercetin-3-glucoside, isorhamnetin-3-glucoside and -3-arabinoside, a somewhat lipophilic kaempferol-3-glucoside derivative, apigenin-7-glucoside, laricitrin-...

Paliurus spina-christi Mill. (Rhamnaceae), also known as Christ's thorn, is a perennial thorny shrub of widespread distribution in dry and rocky places in the Mediterranean region and Asia. In Croatia, this plant grows along the Adriatic coast and on the islands (Polunin and Huxley, 1981). Christ's thorn is used as a diuretic, against diarrhoea and rheumatism in traditional Croatian herbal medi...

DNA topoisomerases are important targets for cancer chemotherapy. We investigated the effects of a methanolic extract of Helichrysum pamphylicum on mammalian DNA topoisomerase I via in vitro plasmid supercoil relaxation assays. The extracts manifested a considerable inhibition of the enzyme's activity in a dose-dependent manner. We also performed a HPLC analysis to identify the flavonoid conten...