Introduction: Cardiac preconditioning represents the most potent and consistently reproducible method of rescuing heart tissue from undergoing irreversible ischemic damage. The aim of the present study was to evaluate oxytocin (OT) induced cardioprotection and its signaling pathways on lactate dehydrogenase (LDH) and creatine kinase-MB isoenzyme (CK-MB) in the anesthetized rats. Methods: Ei...

OBJECTIVES : Pulmonary edema has been shown to occur following ischemiareperfusion injury in a variety of organs and effects of several pharmacological agents on ischemia-reperfusion-induced damage has been investigated previously. However, there are only a few studies in the literature about pulmonary injury following adnexial ischemia-reperfusion. In this study we aimed at investigating pulmo...

Xu Z, Prathapasinghe G, Wu N, Hwang SY, Siow YL, O K. Ischemia-reperfusion reduces cystathionine-synthase-mediated hydrogen sulfide generation in the kidney. Am J Physiol Renal Physiol 297: F27–F35, 2009. First published May 13, 2009; doi:10.1152/ajprenal.00096.2009.—Cystathionine-synthase (CBS) catalyzes the rate-limiting step in the transsulfuration pathway for the metabolism of homocysteine ...

Ischemia-reperfusion injury is a common feature of ischemic stroke, which occurs when blood supply is restored after a period of ischemia. Reperfusion can be achieved either by thrombolysis using thrombolytic reagents such as tissue plasminogen activator (tPA), or through mechanical removal of thrombi. Spontaneous reperfusion also occurs after ischemic stroke. However, despite the beneficial ef...

introduction: cardiac preconditioning represents the most potent and consistently reproducible method of rescuing heart tissue from undergoing irreversible ischemic damage. the aim of the present study was to evaluate oxytocin (ot) induced cardioprotection and its signaling pathways on lactate dehydrogenase (ldh) and creatine kinase-mb isoenzyme (ck-mb) in the anesthetized rats. methods: eighty...

Minekawa, Ryoko, Takashi Takeda, Masahiro Sakata, Masami Hayashi, Aki Isobe, Toshiya Yamamoto, Keiichi Tasaka, and Yuji Murata. Human breast milk suppresses the transcriptional regulation of IL-1 -induced NFB signaling in human intestinal cells. Am J Physiol Cell Physiol 287: C1404–C1411, 2004. First published June 30, 2004; doi:10.1152/ajpcell.00471.2003.—Neonatal necrotizing enterocolitis (NE...