نتایج جستجو برای: ischaemic

تعداد نتایج: 14078  

Journal: :Postgraduate medical journal 2012
Darren Aw Jagdish C Sharma

Antiplatelet therapy has proven efficacy in the secondary prevention of recurrent non-cardioembolic ischaemic stroke. Recent evidence suggests clopidogrel is as effective as combined therapy with aspirin and extended-release dipyridamole for the prevention of recurrent stroke. As cerebrovascular and ischaemic heart disease are closely related, it would be sensible to use a drug shown to prevent...

Journal: :Journal of neurology, neurosurgery, and psychiatry 1989
N Anzalone G Landi

To evaluate the prevalence of lacunar syndromes due to non ischaemic causes 97 consecutive patients with recent (less than 72 hours) onset of a recognised lacunar syndrome were studied. Investigations showed that nine cases were due to non ischaemic pathologies (four primary intracerebral haemorrhages, one rupture of a mycotic aneurysm, one cerebral abscess, one subdural haematoma, one glioblas...

Journal: :British heart journal 1984
C E Handler E Sowton

Diurnal variation and reproducibility of abnormalities occurring during predischarge postinfarction treadmill exercise testing were investigated in 41 patients. Each patient was exercised using a limited Naughton protocol before 0800 and after 1800 h on two consecutive days. No complications arose. Individual ischaemic abnormalities were poorly reproducible in any patient. No abnormality and no...

Journal: :European Heart Journal 2022

Abstract Background Left ventricular thrombus (LVT) may develop in patients following myocardial infarction (MI), as well ischaemic and non-ischaemic cardiomyopathies, result acute stroke. Smaller studies comparing LVT associated with aetiologies only reported 1-year outcomes or focused on specific subpopulations. We aimed to compare the clinical echocardiographic characteristics longer-term a ...

2010
Joanna M. Wardlaw Rüdiger von Kummer Andrew J. Farrall Francesca M. Chappell Michael Hill David Perry

BACKGROUND Early signs of ischaemic stroke on computerised tomography (CT) scanning are subtle but CT is the most widely available diagnostic test for stroke. Scoring methods that code for the extent of brain ischaemia may improve stroke diagnosis and quantification of the impact of ischaemia. METHODOLOGY AND PRINCIPAL FINDINGS We showed CT scans from patients with acute ischaemic stroke (n =...

2003
John C. McGrath Allan MacDonald

Objective: We recently reported the hyper-responsiveness of human skeletal muscle resistance arteries (SkMRAs) to noradrenaline in critical limb ischaemia (CLI). In this study we investigated the characteristics of a -adrenoceptor subtypes and evaluated the agonist 1 affinity and adrenoceptor reserve in the ischaemic arteries. Methods: Human SkMRAs were isolated from non-ischaemic and ischaemic...

Journal: :Cardiovascular research 2015
Waleed G T Masoud Osama Abo Al-Rob Yang Yang Gary D Lopaschuk Alexander S Clanachan

AIMS Post-infarction remodelled failing hearts have reduced metabolic efficiency. Paradoxically, they have increased tolerance to further ischaemic injury. This study was designed to investigate the metabolic mechanisms that may contribute to this phenomenon and to examine the relationship between ischaemic tolerance and metabolic efficiency during post-ischaemic reperfusion. METHODS AND RESU...

Journal: :Journal of Neurology, Neurosurgery & Psychiatry 1994

Journal: :Neurochemistry international 2011
Colin Davidson Ben Coomber Claire L Gibson Andrew M J Young

Fast cyclic voltammetry can be used to measure dopamine release after oxygen and glucose deprivation (OGD) induced anoxic depolarization in vitro. Here we measure dopamine efflux with 1s time resolution, which is appropriate to measure OGD-evoked dopamine efflux accurately. In the present study, we examined whether OGD-evoked dopamine efflux could be used to show pre-ischaemic conditioning in t...

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