Acinetobacter baumannii has emerged as an important opportunistic pathogen due to its ability to acquire resistance to most currently available antibiotics. Colistin is often considered as the last line of therapy for infections caused by multidrug-resistant A. baumannii (MDRAB). However, colistin-resistant A. baumannii strain has recently been reported. To explore how multiple drug-resistant A...

Acinetobacter baumannii is one of the most important nosocomial pathogen worldwide. This study aimed to investigate virulence potential and genomic relatedness A. strains isolated from patients hospitalized in Military Medical Academy (MMA) by detecting OXA-type carbapenemases genes, biofilm-associated RAPD analysis. PCR was used detect blaoxa ISAba-1 genetic element, genes. The determined anal...

Carbapenem-resistant Acinetobacter baumannii has been considered one of the major threats to patients worldwide. To evaluate carbapenemase in several clinical isolates using phenotypic and genotypic approaches. A total 49 A. were tested against imipenem meropenem discs on Muller Hinton agar, then screened phenotypically through modified Hodge test (MHT), combined disc (CDT) carbapenem inactivat...

Sir, In Acinetobacter baumannii, resistance to third-generation cephalosporins such as ceftazidime and cefotaxime is known to arise as a consequence of acquisition of an insertion sequence, ISAba1, upstream of the chromosomal ampC gene. Indeed, ISAba1 is frequently found upstream of the ampC gene in isolates that are resistant to third-generation cephalosporins, and the promoter that directs tr...

Introduction: Infections caused by carbapenem-resistant Acinetobacter baumannii(CRAB) is a health problem due to the limited therapeutic options available. This study was carried out evaluate main mechanisms of resistance carbapenems in CRAB last 10 years Brazil and describe susceptibility profile tigecycline polymyxins these isolates. Material methods: A systematic review according Prisma PUBM...

OBJECTIVES to investigate the epidemiological traits of carbapenem-non-susceptible Acinetobacter baumannii (CNSAB) and the usefulness of phylogenetic grouping based on partial rpoB gene sequencing in defining the epidemiological traits of CNSAB. METHODS a total of 547 non-duplicate clinical isolates of Acinetobacter spp. were collected from 19 hospitals in Korea in 2008. Detection of genes en...