BACKGROUND AND AIM Small intestinal bacterial overgrowth is encountered in bowel disorders, including irritable bowel symptoms. Low degrees of inflammation have been recently reported in the irritable bowel syndrome. We looked for the association between intestinal inflammation and small intestinal bacterial overgrowth in irritable bowel syndrome. METHODS Small intestinal bacterial overgrowth...

AIM The aim of this study was to assess the incidence of irritable bowel syndrome in women undergoing hysterectomy and tubular ligation. BACKGROUND The results of previous studies have shown an increased incidence of irritable bowel syndrome after gynecological surgeries. PATIENTS AND METHODS Participants were patients of Alzahra and Taleghani University hospitals in Tabriz. One hundred and...

Both irritable bowel syndrome and endometriosis are common conditions, although symptomatic gastrointestinal endometriosis is extremely rare. We report the case of a patient initially thought to have irritable bowel syndrome, in whom the diagnosis of endometriosis only became clear following a laparotomy for small bowel obstruction. This case highlights the need to question the diagnosis in pat...

BACKGROUND Alosetron is a potent and selective 5-HT3 receptor antagonist, which has been shown to be beneficial in the treatment of female patients with non-constipated irritable bowel syndrome. AIMS To investigate the effect of alosetron on whole gut, small bowel and colonic transit in patients with irritable bowel syndrome (Study 1) and healthy volunteers (Study 2). SUBJECTS Thirteen pati...

BACKGROUND AND PURPOSE Functional neuroimaging studies in irritable bowel syndrome have revealed abnormalities in the corticolimbic regions, specifically, hyperactivity of the amygdala during visceral and somatic stimulation. This study investigated changes in the neural circuitry of the amygdala in patients with irritable bowel syndrome based on resting-state functional connectivity. MATERIA...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: irritable bowel syndrome (ibs) is one of the most common functional gastrointestinal disorders presented by bowel habit change and abdominal pain without any structural defect. prevalence of ibs in iran was reported between 4.2-18.4%. although the etiology is still unknown but many factors such as motility diso...

background: migraine and irritable bowel syndrome (ibs) are chronic conditions that seem to share common pathophysiological aspects. objectives: our study aimed to estimate the prevalence of ibs in an iranian migraine population, investigate its association with headache's characteristics and depression. materials and methods: this cross-sectional study was done in a tertiary hospital clin...

BACKGROUND ONO-2952 is a novel and selective inhibitor of translocator protein 18 kDa that reduces stress-induced defecation and visceral hyperalgesia in rat models. AIM To evaluate the efficacy and safety of ONO-2952 in females with irritable bowel syndrome with diarrhoea in an exploratory proof-of-concept study. METHODS A randomised, double-blind, placebo-controlled study was conducted at...

background and objective : irritable bowel syndrome (ibs) is a functional gastrointestinal disorder. sleep disturb-ances are known to be common among individuals with this syndrome. this study aimed to determine the relationship between sleep quality and severity of intestinal symptoms in irritable bowel syndrome. materials and methods : this cross-sectional study was carried out among 201 subj...