Indoor residual spraying with DDT was the principle method by which malaria transmission was eradicated or greatly reduced in many countries between the late 1940s and 1970s. Since then, decreasing use of DDT has been associated with a resurgence of malaria in India, Sri Lanka, former Soviet Central Asia, Zanzibar, Venezuela and several other Latin American countries. In India and Zanzibar, DDT...

Objective: The present study aimed to investigate the relationships between anxiety sensitivity (AS), irritability and intrusive thoughts (IT) and sleep problems in patients diagnosed with generalized anxiety disorder (GAD). Methods: The study population consisted of all patients with GAD who referred to counseling and psychological centers in Isfahan, Iran, in 2015. A total of 49 patients wer...

We investigated the tissue-specific effects of dichlorodyphenyltrichloroethane (DDT) isomers in adult and suckling newborn mice, using a novel mouse line engineered to express a reporter of estrogen receptor transcriptional activity (ERE-tkLUC mouse). The DDT isomers p,p'-DDT [1,1,1-trichloro2,2-bis(p-chlorophenyl) ethane] and o,p'-DDT [1,1,1-trichloro-2(p-chlorophenyl)-2-(o-chlorophenyl) ethan...

susceptibility status of ph.papatasi to ddt 4% has been evaluated in arsanjan country, the new focus of cutaneous leishmaniasis, in fars province in 1999. sandflies were collected from human habitations. tests revealed that this species was sensitive to ddt. results from data analysis showed that lt50 and lt90 can be measured as 30 (fiducially limit; 23, 36) and 55 minutes (fiducially limit: 44...

BACKGROUND Although dichlorodiphenyl trichloroethane (DDT) exposure is known to affect human endocrine function, few previous studies have investigated the effects of DDT exposure on age at menarche or menstrual cycle length. METHODS A cross sectional study was conducted to study the effects of DDT exposure on age at menarche and menstrual cycle length among 466 newly married, nulliparous fem...

The DDT i nh ibition of (Na+, K+) a ctivated ATPase in gill pre parations of the euryhaline teleost , Fundulus heteroclitus, was measured. The (Na+, K+) -activate d ATPase was found to be sensitive to DDT, with 74.6% of the e nzyme's specific activity inhibited by 20 ppm DDT . The (Mg++)-activated ATPase was also sensitive to inhibition bv DDT but not to the extent of the (Na+, K+) activat ed A...

The development of resistance to insecticides has become a classic exemplar of evolution occurring within human time scales. In this study we demonstrate how resistance to DDT in the major African malaria vector Anopheles gambiae is a result of both target-site resistance mechanisms that have introgressed between incipient species (the M- and S-molecular forms) and allelic variants in a DDT-det...

Title of Document: FACTORS RELATED TO CHANGES IN INFANT ATTACHMENT SECURITY: A TEST OF THE DIFFERENTIAL SUSCEPTIBILITY HYPOTHESIS Brandi Shawn Stupica, Master of Science, 2009 Directed By: Professor Jude Cassidy, Department of Psychology A major tenet of attachment theory is that the stability of the caregiving environment drives the stability of infant attachment security. The research investi...

We previously demonstrated a good correlation between the increased relative liver weight caused by DDT and the area under the concentration-time curve (AUC) of DDT or the total DDT (T-DDT) in plasma and liver of rats in a 7-day repeated dose study at 1000 ppm. To confirm the reliability of AUC for predicting toxic responses at different dose levels, we conducted a further 28-day repeated dose ...