Abstract Background This study intends to investigate the immunological effects of tumor ablation with irreversible electroporation (IRE). Methods We evaluated systemic immune response in patients hepatocellular carcinoma (HCC) after IRE treatment. Furthermore, we analyzed infiltrating T lymphocytes and level serum cytokines control groups tumor-bearing mice. Results observed that induced an in...

The objective of this chapter is to present a historical review of the field of irreversible electroporation (IRE) in the context of its medical applications. Although relevant scientific observations were made since the 18 th century, the electroporation phenomenon was not identified as an increase of membrane permeability until mid 20 th century. After that, multiple applications of reversibl...

One recent area of cancer research is irreversible electroporation (IRE). Irreversible electroporation is a minimally invasive procedure where needle electrodes are inserted into the body to ablate tumor cells with electricity. The aim of this paper is to investigate how uncertainty in tissue and tumor conductivity propagate into final ablation predictions used for treatment planning. Two dimen...

The objective of this chapter is to present a historical review of the field of irreversible electroporation (IRE) in the context of its medical applications. Although relevant scientific observations were made since the 18 th century, the electroporation phenomenon was not identified as an increase of membrane permeability until mid 20 th century. After that, multiple applications of reversibl...