Two phenylpropanoid-conjugated iridoids, deglucosyl gaertneroside (1) and morindoidin (2), were isolated from the leaves of Morinda morindoides (Rubiaceae) by activity-guided fractionation using an anti-malarial activity assay. The known related iridoids molucidin (3) prismatomerin (4), two lignans, abscisic acid, megastigmanes, flavonol glycosides also identified. structures compounds elucidat...

COVID-19 is a global pandemic that has claimed millions of lives. This disease caused by coronavirus, SARS-CoV-2, which requires the binding its spike protein to angiotensin-converting enzyme 2 (ACE2) for infection host cell. Morinda citrifolia (noni) fruit juice antiviral activity involves enhancement immune system function. SARS-CoV-2 spike-ACE2 interaction experiments were carried out furthe...

Five new iridoids, salvialosides A-E (compounds 1-5), together with fifty known compounds were isolated from the roots of Salvia digitaloides. The structures of the new compounds were completely elucidated using a combination of 2D NMR techniques (COSY, NOESY, HMQC and HMBC) and HR-ESI-MS analyses. The known compounds were identified by comparison of their spectroscopic and physical data with t...

Mussaenda 'dona aurora' (sepals) has been investigated for its hepatoprotective and antioxidant activities. The highest activity was observed in the ethyl acetate fraction. The separation of the ethyl acetate fraction gave two iridoids, sanshiside-D and lamalbide. Sanshiside-D exhibited a hepatoprotective activity greater than silimarin as was evidenced by significant reduction of ALT and AST i...