background il28b polymorphism is recognized as one of the most prominent predictors of hepatitis c spontaneous and treatment-induced clearance. interestingly, the favorable genotypes of il28b are found to be more frequent in asian ethnicity than caucasian and african populations, respectively. a few studies reported that there is a mysterious association between the il28b polymorphism and the h...

the pathogenesis of bipolar i disorder (bp-i) involves immune-mediated mechanisms, especially an imbalance in pro-inflammatory/anti-inflammatory cytokines in plasma or cerebrospinal fluid. interleukin-1 (il-1) gene cluster, coding some of these pro-inflammatory cytokines, might play a role in various neuropathologies related to neuron inflammation. the aim of the present study was to investigat...

In this paper we propose a conditional logic IBC to represent iterated belief revision. We define an iterated belief revision system by strengthening the postulates proposed by Darwiche and Pearl [3]. First, following the line of Darwiche and Pearl, we modify AGM postulates to make belief revision a function of epistemic states rather than of belief sets. Then we propose a set of postulates for...

Abstract Background Acute myocardial infarction (AMI) is a leading cause of death and morbidity around the world. Although association between thrombophilia AMI well-established, controversial data are present on thrombophilic polymorphisms AMI. The aim this study was to investigate three including factor V Leiden ( FVL ), MTHFRC677T (methylenetetrahydrofolate reductase), Coagulation XIIIVal34L...

AIM The present study evaluated the association between G241R and K469E polymorphisms of intercellular adhesion molecule 1 gene and inflammatory bowel disease in Iranian population. BACKGROUND Inflammatory bowel disease including ulcerative colitis and Crohn's disease, is a chronic idiopathic inflammatory disease of the gastrointestinal tract. There are two single base polymorphisms of interc...

Background: Lung cancer is the most common with 2,206,771 new cases in 2020 worldwide. MMP9 a member of matrix metalloproteinase family that also known as gelatinase B or IV type collagenase (92KD). through degrading Extracellular Matrix (ECM) and releasing growth factors has fundamental role tumorigenesis process. The C -1562 T SNP promoter increases expression susceptibility to lung cancer. T...

BACKGROUND Hepatitis delta virus (HDV) is dependent on the hepatitis B virus for transmission and propagation. Based on isolated HDV sequences from different parts of the world, at least three major different genotypes with different geographic distributions are suggested. Studies have shown that genotype 1 is the predominant genotype of HDV in different parts of Iran; however, the genotype dis...

Abstract Background Interleukin (IL)-10 is one of the key interleukins in immune system. It plays an anti-inflammatory role body by inhibition synthesis pro-inflammatory cytokines and reducing expression major histocompatibility complex II molecules. The single-nucleotide polymorphism gene this interleukin affects its level. Thus, study was conducted to investigate IL-10 at position -1082A/G Az...

BACKGROUND Von Willebrand disease (VWD) is an autosomal recessive congenital bleeding disorder with deficiency or dysfunction of von Willebrand factor (VWF). The gene encoding for the VWF is located on chromosome 12, which is 178 Kb with 52 exons. Various mutations of this gene is responsible for the clinical features of VWD, but some single nucleotide polymorphisms make the molecular diagnosis...