This review of atmospheric pressure ion sources discusses major developments that have occurred since 1991. Advances in the instrumentation and understanding of the key physical principles are the primary focus. Developments with electrospray and atmospheric pressure chemical ionization and variations encompassing adaptations for surface analysis, ambient air analysis, high throughput, and modi...

Using a combination of semiclassical and recently developed wave packet propagation techniques we find the quantum self-ionization process of highly excited ions moving in magnetic fields which has its origin in the energy transfer from the center of mass to the electronic motion. It obeys a time scale orders of magnitude larger than the corresponding classical process. Importantly a quantum co...

Coherent control techniques are computationally applied to cold (1 mK<T<1 K) and ultracold (T<1 muK) Ne*(3s,3P2)+Ar(1S0) collisions. We show that by using various initial superpositions of the Ne*(3s,3P2) M={-2,-1,0,1,2} Zeeman sublevels it is possible to reduce the Penning ionization and associative ionization cross sections by as much as 4 orders of magnitude. It is also possible to drastical...

time-dependent schrödinger equation for a 1-d model of hydrogen molecular ion h2+ in intenselaser field linearly polarized along the molecular axis is solved. ionization rates are calculated for differentinitial states. the evolution of electronic wavefunction at fixed inter-nuclear separations are simulated andanalyzed. the results obtained for the ground state of this 1-d model of h2+ show ap...

This review highlights and critically assesses forensic applications in the developing field of ambient ionization mass spectrometry. Ambient ionization methods permit the ionization of samples outside the mass spectrometer in the ordinary atmosphere, with minimal sample preparation. Several ambient ionization methods have been created since 2004 and they utilize different mechanisms to create ...

High-performance polymers are complex mixtures of materials of different size and chemical composition and with different end groups and architecture. To determine the molecular heterogeneity of such systems, hyphenation of several techniques is required. The value of coupling mass spectrometry (MS) with separation techniques has already been recognized - such methods have proved to be among th...

The study of the metabolic fate of drugs is an essential and important part of the drug development process. The analysis of metabolites is a challenging task and several different analytical methods have been used in these studies. However, after the introduction of the atmospheric pressure ionization (API) technique, electrospray and atmospheric pressure chemical ionization, liquid chromatogr...

This review outlines the use of modern methods of mass spectrometry, mainly based on electrospray ionization and matrix-assisted lased desorption/ionization, for the identification of protein-bound carbohydrates. The techniques are briefly described together with methods for glycan release and purification prior to mass spectrometry. Fragmentation of glycans, produced under various conditions, ...