In this paper we illustrate the architecture and the main features of a bio-inspired control system employed to govern an anthropomorphic artificial Arm. The manipulation system we developed was designed starting from a deeply study of the human limb from the anatomical, physiological and neurological point of view. In accordance with the general view of the Biorobotics field we try to replicat...

Calcium phosphate coating (CaP) has been employed for protein delivery, but the typical direct protein adsorption on the coating led to low incorporation content and fast release of the protein from the coating. By using bovine serum albumin (BSA) as a model protein, rapid biomimetic co-precipitation between calcium phosphate and BSA was employed to control the distribution of BSA within calciu...

Maintaining activity of enzymes tethered to solid interfaces remains a major challenge in developing hybrid organic-inorganic devices. In nature, mammalian spermatozoa have overcome this design challenge by having glycolytic enzymes with specialized targeting domains that enable them to function while tethered to a cytoskeletal element. As a step toward designing a hybrid organic-inorganic ATP-...

Biomimetic calcium phosphate coatings have been developed for bone regeneration and repair because of their biocompatibility, osteoconductivity, and easy preparation. They can be rendered osteoinductive by incorporating an osteogenic agent, such as bone morphogenetic protein 2 (BMP-2), into the crystalline lattice work in physiological situations. The biomimetic calcium phosphate coating enable...

The repair of critical-sized bone defects is still challenging in the fields of implantology, maxillofacial surgery and orthopaedics. Current therapies such as autografts and allografts are associated with various limitations. Cytokine-based bone tissue engineering has been attracting increasing attention. Bone-inducing agents have been locally injected to stimulate the native bone-formation ac...

2 Brain-machine interfaces rely on extracting motor control signals from brain activity in real time 3 to actuate external devices such as robotic limbs. Whereas biomimetic approaches to neural 4 decoding use motor imagery/observation signals, non-biomimetic approaches assign an arbi5 trary transformation that maps neural activity to motor control signals. In this work, we present 6 a unified f...

Biomimetic polymer networks have been developed with tailored affinities and transport properties for a given target molecule, and these networks promise to significantly impact a wide variety of biomedical fields, including controlled drug delivery and biosensing. Biosensors typically employ biological compounds as recognition elements, and biomimetic artificial networks would be advantageous ...

Treatment of large bone defects using synthetic scaffolds remain a challenge mainly due to insufficient vascularization. This study is to engineer a vascularized bone graft by integrating a vascularized biomimetic cell-sheet-engineered periosteum (CSEP) and a biodegradable macroporous beta-tricalcium phosphate (β-TCP) scaffold. We first cultured human mesenchymal stem cells (hMSCs) to form cell...

Biomimetic mineralisation is an alternative restorative methodology that imitates the natural process of mineralisation. We aimed to systematically review the laboratory methods on the biomimetic mineralisation of demineralised enamel. A search in the PubMed, ScienceDirect, and ISI Web of Science databases was performed. Clinical trials, reviews, non-English articles, animal teeth, non-tooth su...