the dynamic facility layout problem (dflp) is the problem of finding positions of departments onthe plant floor for multiple periods (material flows between departments change during the planning horizon)such that departments do not overlap, and the sum of the material handling and rearrangement costs isminimized. in this paper a new optimization algorithm inspired from colonizing weeds, invasi...

in human breast cancer, estrogen receptor (er) status of the tumor has prognostic and therapeutic significance. however, facilities to study er are not widely available to us. we postulated that if there is a correlation between histologic grade and er status of invasive ductal carcinoma (idc), it may help predict the er status of the tumor. of 8 4 cases of breast carcinoma referred to the canc...

background & aim : neonatal period is one of the most high-risk stages of human life affected by some factors associated to pre- and post-delivery stages, such as invasive procedures. anxiety is found to be one of the most common psychological disorders during prenatal period, especially the third trimester. until now, significant negative consequences of anxiety on newborn’s health are reporte...

background: an early diagnosis of breast cancer relates directly to an accurate treatment plan and strategy. early detection of breast cancer before its development would be a significant reduction of morbidity and mortality rates. the aim of this preliminary study is to investigate the sensitivity of wide angle x-ray diffraction (waxrd) method on women hair samples of healthy and breast cancer...

cardiovascular disease remains the principal cause of death in the modernized world.   several novel noninvasive imaging techniques have been recently developed to improve diagnosis of cardiac and coronary disease.   of these advances, multidetector computed tomographic (mdct) angiography has evolved most dramatically to transform computed tomography from a single-slice trans-axial modality to ...

hemodynamic monitoring is needed in up to 58% of patients presented to the emergency department. central venous pressure (cvp) monitoring is generally useful to assess general volume status. there are several methods of cvp measurement, which can be categorized as invasive and non-invasive. cvp manometer and electronic transducer are among the invasive methods and direct observation, ultrasonog...

This article reviews the development of non-invasive optical techniques for determination of blood glucose concentrations in diabetic patients. Early diagnosis and daily management are essential for ensuring the healthy life of diabetic patients. The determination of blood glucose concentration with common devices involves the chemical analysis of blood samples, which are obtained by pricking t...

The frequency of use of systemic antifungal agents has increased significantly in most tertiary centers. However, antifungal stewardship has received very little attention. The objective of this article was to assess the knowledge of prescribing physicians in our institution as a first step in the development of an antifungal stewardship program. Attending physicians from the departments that p...

background and purpose: invasive aspergillosis (ia) is one of the most common life-threatening fungal infections among the critically ill patients including intensive care unit (icu) patients. delayed diagnosis and therapy may lead to poor outcomes. diagnosis may be facilitated by a test for molecular biomarkers, i.e. detection of galactomannan (gm) antigen based on enzyme immunoassay, which is...

wound complications following ankle fracture surgery are a major concern. through the use of minimally invasive surgical techniques some of these complications can be mitigated. recent investigations have reported on percutaneous fixation of distal fibula fractures demonstrating similar radiographic and functional outcomes to traditional open approaches. the purpose of this manuscript is to des...