Intravenous immunoglobulin (IVIg) is concentrated human immunoglobulins made from pooled donor plasma. Commercial preparations were used for clinical administration since early 1980s [1]. It modulates the immune response in a variety of inflammatory and autoimmune disorders. Although high-dose IVIg generally is considered safe, it is not without side effects and may promote life-threatening thr...

Intravenous immunoglobulin (IVIG) concentrates were originally developed as replacement therapy for individuals with primary deficiencies of the immune system. However, in various well-designed, controlled clinical trials, the ability of IVIG to prevent and possibly treat infections in patients with secondary immune deficiencies has also been considered. In this review, we briefly consider thes...

Objective: Recurrent pregnancy loss is a global issue. This study was planned in order to evaluate the effects of high dose intravenous immunoglobulin (IV Ig) in primary and secondary unexplained miscarriages in patients of recurrent pregnancy loss. Patients and Methods: Total 168 couples having history of primary or secondary recurrent pregnancy loss were included in the study. They were divid...

OBJECTIVE The objective of the study was to profile leukocyte markers modulated during intravenous immunoglobulin (IVIg) treatment, and to identify markers and immune pathways associated with clinical efficacy of IVIg for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) with potential for monitoring treatment efficacy. METHODS Response to IVIg treatment in newly diagnosed IVIg...

long-term intravenous immunoglobulin (ivig) infusion is an effective treatment for children with humoral immunodeficiencies, already be complicated by systemic ad¬verse effects. in order to determine the adverse effects of intravenous immunoglobulin inpatients with antibody deficiency, 45 immunodeficientpatients receiving intravenous immunoglobulin were studied during a 36-month period at child...

Intravenous immunoglobulin (IVIG) is commonly used for a wide range of diagnoses, by multiple pediatric subspecialists. We report two cases of hepatitis B screening results post IVIG infusion, where positive anti-Hepatitis B core antigen serology tests indicated possible occult hepatitis infection, leading to a delay in care. However, serial antibody testing showed results consistent with the p...

Intravenous immunoglobulin (IVIG) is a blood product prepared from the serum of of a thousand or more blood donors. The IVIG that is available contains complete immunoglobulin G( IgG )molecules which has intact Fc-dependent effector functions. The IgG subclasses match those in normal human serum. It is the main treatment for patients with antibody deficiencies. High dose IVIG (hdIVIG), is used ...

Intravenous immunoglobulin (IVIg) is used to treat a number of immune deficiencies and autoimmune diseases. The pharmacokinetic proprieties of IVIg in healthy persons are well defined. The broad range of clinical applications of IVIg shows the importance of immunoglobulins in the immune homeostasis in healthy people. Intravenous immunoglobulin (IVIg) is an immunomodulating agent that has multip...

Intravenous immunoglobulin Furusho et al.1) first administered high-dose intravenous immunoglobulin (IVIG) to patients with Kawasaki disease (KD) in the early 1980s. This trial was inspired by the report that high-dose IVIG therapy was very effective for idiopathic thrombocytopenic purpura2) and that its potential mechanism of action was immunomodulation. At that time, Furusho et al.1) suggeste...

Background: Patients with Kawasaki disease (KD) are at a significantly increased risk of allergic diseases. Immunoglobulin E (IgE) is an immunoglobulin that mediates sensitization to various allergens and related However, few studies have analyzed specific IgE on allergy biomarkers after KD diagnosed. Objective: This study aimed investigate the pattern levels against food inhalant allergens. Me...