estimated to affect 170 million people worldwide and 20%-30% of these will eventually progress to liver cirrhosis and its sequelae, such as hepatocellular carcinoma.1 In the Kingdom of Saudi Arabia (KSA) sero-prevalence studies suggest that the overall antiHCV positivity is 0.99%, while in subjects over the age of 50 years it is 3.5%-5%.2,3 This prevalence rises to 75% among intravenous drug us...

A previously healthy 31-year-old man was referred to us with refractory septic shock accompanied by bilateral conjunctival congestion and erythema of his right lower limb. Nine days after admission, he had bilateral desquamation of the fingertips, and his presentation satisfied the criteria for Kawasaki disease. A serological examination was positive for Yersinia pseudotuberculosis, and he was ...

SOME years ago the senior author publicly expressed [l] the hypothesis that women with rheumatoid arthritis should, with undue frequency, be married to men with peptic ulcers. The reason given for this speculation was that it seemed likely that the hostility in these marriages [2, 31 would leave unmet the husbands’ needs for emotional support and the wives’ needs for ego support. When in the co...

A method for estimating intrafamilial correlations under variable family sizes involving weightings of paired data points is introduced. Classical methods of intrafamilial correlation estimation and those in current use are outlined and critically analyzed. Extensions of the proposed estimation method to more general data structures are delineated.

Shigellosis epidemics were investigated in two urban centers. In each city, preschool children played a major role in O!fecting their families and were most susceptible to secondary infection after illness had been introduced into the household. Children attending day-care centers were significantly more likely to be initial cases and to be the major cause of intrafamilial spread of disease tha...