Introduction MRI semiotics in the differential diagnosis of primary extra-axial intracranial tumors (PEIT) Localization tumor and its relationship with anatomical structures Heterogeneity (heterogeneity) Tumor margins peritumoral edema Apparent diffusion coefficient (ADC) Dural tail sign Information technology for analysis radiomics Radiomics PEIT Conclusion

Meningiomas are the tumors which are found in cases of multiple intracranial tumors of different histology. This is attributed to frequent occurrence of intracranial meningiomas and their long clinical evolution before diagnosis. Thus, they have an increased probability of simultaneously harboring another primary or secondary intracranial tumors. Central nervous system (CNS) melanotic tumors in...

Aims: Trigeminal neuralgia is generally caused by neurovascular compression. In rare cases intracranial tumors may also lead to this condition. The present study was conducted to identify clinical symptoms and testing methods that are useful for early detection of trigeminal neuralgia associated with intracranial tumor. Methods: Five patients with trigeminal neuralgia suspected to be due to int...

BACKGROUND Patients presenting with synchronous bifocal intracranial tumors (masses in the pineal and neurohypophyseal region), detectable human chorionic gonadotropin (hCG) levels (5-100 mIU/mL), and normal alpha feto-protein (AFP) levels (≤10 ng/mL) are often diagnosed empirically with pure germinoma. In such scenarios, pathologic confirmation is often deferred, given that bifocal nongerminom...

Newborn mice of C3Hf/Bi (Zb) strain were divided into three groups and injected, intracranially with adenovirus type 12 alone, subcutaneously with 20 mgjkg of N, N’-dimethylnitrosourea following intracranial inoculation of adenovirus type 12, and subcutaneously with 20 mgjkg of N, N’-dimethylnitrosourea alone at 10 days of age, respectively. With adenovirus type 12 alone, intracranial tumors we...

BACKGROUND Congenital hemangiomas are benign vascular tumors, and the intracranial counterpart was described in very few cases. CASE DESCRIPTION A newborn presented with an intracranial tumor associated with an arachnoid cyst, diagnosed by antenatal ultrasound at 37 weeks of gestation. Surgery was indicated due to increased head circumference and bulging fontanelle, and a complete resection o...

Epidermal growth factor receptor (EGFR) is amplified or overexpressed in many malignant gliomas and other primary brain tumors but is low or undetectable in normal brain. In the present study, this differential expression has been exploited for targeted brain tumor therapy using a TGF-alpha-Pseudomonas exotoxin recombinant toxin, TGF-alpha-PE38. In vitro experiments demonstrate that the cytotox...