Direct measurements of arterial blood pressure and intracranial pressure were recorded in 39 patients aged 3.6 months to 5 years 11 months with Reye's syndrome judged to be stage 2 or beyond. Of 33 patients who survived, 27 made a full recovery and six were severely handicapped. Measurement of cerebral perfusion pressure, which is greatly reduced in the more severe forms of Reye's syndrome, was...

BACKGROUND Hyperthermia is a common secondary insult in traumatic brain injury (TBI). The aim was to evaluate the relationship between hyperthermia and intracranial pressure (ICP), and if intracranial compliance and cerebral blood flow (CBF) pressure autoregulation affected that relationship. The relationships between hyperthermia and cerebral oximetry (BtipO2) and cerebral metabolism were also...

abstract meningeal melanocytoma is a rare tumor of nervous system, which originates from leptomeningeal melanocytes. the locations of melanocytoma in the nervous system are most frequently in the posterior fossa or along the spinal cord, and usually appear as an extra-axial mass. the manifestations of tumor are most often due to its compressing effect on adjacent nervous structures that causes ...

a 34 day-old girl infant was admitted for poor feeding and cholestasis. she had a bulging fontanelle, with no evidence of intracranial infection or hemorrhage. investigations demonstrated that she had galactosemia. computed tomographic scans demonstrated the presence of diffuse cerebral edema. after treatment the edema resolved.

Background. The increase of the optic nerve sheath diameter (ONSD) is a reliable, noninvasive sonographic marker of intracranial hypertension. Aim of the study was to demonstrate the efficacy of ONSD evaluation, when monitoring neurocritical patients, to early identify malignant intracranial hypertension in patients with brain death (BD). Methods. Data from ultrasound ONSD evaluation have been ...

OBJECTIVE To evaluate the effect of intermittent pneumatic leg compression on intracranial pressure and cerebral perfusion pressure in brain-injured patients. DESIGN Prospective, sequential patient study. SETTING Surgical/trauma ICU of a community hospital providing regional trauma care. PATIENTS Twenty-four adult, brain-injured patients (mean Glasgow Coma Scale score = 6) who required he...