Familial hyperproinsulinemia is an autosomal dominant defect that is associated with strikingly elevated levels of serum proinsulin-like material. Our studies show that trypsin converts familial hyperproinsulinemia proinsulin to insulin more slowly than it converts a 131I-labeled porcine proinsulin marker. Molar yields of insulin indicated that the material may be an intermediate proinsulin. St...

Intra-abdominal desmoid tumors are commonly associated with genetic syndromes such as familial polyposis coli. Radiological cross imaging studies such as CT and MRI are used in the preoperative work-up of such tumors. Postoperatively, CT and MRI are useful in the assessment of recurrent desmoid tumors. MRI is more accurate in tissue characterization. Where possible, surgical resection remains t...

Intra-abdominal fibromatosis (IAF) may arise either sporadically or in association with familial adenomatous polyposis. The characteristics of fibromatosis are slow-growth, benign histological features, and aggressive local invasion. Surgery remains a reasonable first treatment option. Here, we report 2 cases of a phenomenon rarely described in published literature, IAF after gastrectomy for ga...

We propose a structural econometric model that incorporates altruism towards other household members into the willingness to pay for public good. The distinguishes preferences good improvements oneself from members. test three different types of - ‘pure self-interest’, altruism’ and ‘public-good-focused non-pure altruism’. Using French contingent valuation data regarding air quality improvement...

Pulmonary alveolar microlithiasis (PAM) is a rare disease of unknown etiology characterized by intra-alveolar calcium deposits. More than 500 cases were reported in the literature. The disorder affects people at every age beginning from the early childhood. It occurs probably as a result of autosomal recessive transmission. Familial occurrence is often found with family history of the disease b...

The first description of oral lipomas was made by Roux in 1848. He referred it as a ‘yellow Epulis’ [4]. Morphologically intra-oral lipomas can be classified as diffuse form affecting the deeper tissues, superficial form and encapsulated form [5]. Multiple head and neck lipomas have been observed in neurofibromatosis, Gardner syndrome, EcephaloCraniocutaneous lipomatosis, Multiple familial lipo...