Mucinous adenocarcinoma (MC) is a unique pathological type of colorectal cancer (CRC). The development of MC is often associated with intestinal inflammation and/or microsatellite instability (MSI). Moreover, MC has clinicopathological characteristics that render making the correct diagnosis difficult such as extramural progression. Meanwhile, intestinal spirochetosis (IS) is a condition in whi...

The early work on intestinal lactase has been reviewed by Plimmer (1906) and Oppenheimer (1925). No uniformity of opinion was reached regarding the presence and dist,ribution of this enzyme in the intestinal mucosa or in intestinal juice. Without attempting to review these investigations again, it suffices to state that some authors found lactase in the small intestine of young animals. Others ...

Background We previously reported that the mouse Ly6/Plaur domain containing 8 (mLypd8), a GPI-anchored protein highly and selectively expressed on colonic epithelia, contributes to segregation of intestinal microbiota and intestinal epithelia and is critical for prevention of intestinal inflammation. In addition, it was found that human LYPD8 (hLYPD8) is expressed in the colonic epithelia and ...

Oral absorption of compounds depends on many physiological, physiochemical and formulation factors. Two important properties that govern oral absorption are in vitro permeability and solubility, which are commonly used as indicators of human intestinal absorption. Despite this, the nature and exact characteristics of the relationship between these parameters are not well understood. In this stu...

the prevalence of various intestinal helminthiasis have been determined by the examination of 8109 inhabitants of 20 villages located in the mountainous and coastal regions of the bandar abbas and minab areas in southern iran. a portion of people infected with each parasite were treated with the appropriate drug i and the worms expelled were collected, identified and counted. the results indica...

background: acute obstruction of the colon continues to be a lethal disease with little improvement in the mortality rate over the past 50 years. so, this study was undertaken to define the causes of colon obstruction and their probable changes after years. â  methods: from 1979 to 2004, all records of patients with definite diagnosis of intestinal obstruction at all hospitals affiliated to shi...

In contrast to the extensively reported therapeutic activities, far less attention has been paid to the intestinal absorption of the total saponins from Radix Ilicis Pubescentis (in Chinese Mao-Dong-Qing, MDQ). This study aimed to investigate the intestinal absorption characteristics of ilexgenin A (C1), ilexsaponin A1 (C2), ilexsaponin B1 (C3), ilexsaponin B2 (C4), ilexsaponin B3 (DC1), and il...

The present study is focused on the intestinal absorption of sea cucumber saponins. We determined the pharmacokinetic characteristics and bioavailability of Echinoside A and Holotoxin A₁; the findings indicated that the bioavailability of Holotoxin A₁ was lower than Echinoside A. We inferred that the differences in chemical structure between compounds was a factor that explained their different...