background: giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. giant cell tumor (gct) of the sphenoid bone is relatively rare. in this report, we describe a tumor of the greater wing of left sphenoid bone. case presentation: a 31-year-old female was presented with headache, proptosis and diplopia of her left eye. cranial magnetic resonance ima...

introduction: granular cell tumors (gcts) are rare and mostly benign soft tissue tumors. though they have been reported in all parts of body, they are generally located in the head and neck region, especially on the tongue. some malign forms exist, but these have been rarely reported. granular cell tumors have a neural origin and, in immunohistochemical evaluations, they express s-100 and neuro...

Antigenic specificities and cross-reactivities of rat tumor cells were explored with rabbit antisera raised against a biochemically differentiated ethylnitrosourea-induced rat schwannoma cell clone, SCHW-RN-2. The hyperimmune anti-SCHW-RN-2 antisera were used to analyze the antigens of viable monolayers of rat cell cultures by an indirect sequential adsorption radioimmunoassay. Exhaustive mul t...

sertoli cell tumors of the testis are extremely rare tumors with a heterogeneous pathology. three histological variants have been described: sertoli cell tumor not otherwise specified (nos), large cell calcifying sertoli cell tumor and the sclerosing sertoli cell tumor. the sclerosing sertoli cell tumor described herein is associated with prominent stromal sclerosis. they present as painless sc...

Introduction: Renomedullary interstitial cell tumors are benign of renal medulla. They usually asymptomatic, and preoperative diagnosis based on radiological findings is challenging. Therefore, in most clinical situations, nephrectomy ultimately performed for differential diagnosis. Case Presentation: A 54-year-old woman presented to our hospital with hematuria. An incidental mass the left kidn...

A full-length complementary DNA (cDNA) for interstitial collagenase was isolated from an A2058 melanoma cDNA library using the pCD-X Okayama-Berg vector. The tumor interstitial collagenase cDNA was sequenced and compared to the published sequences for human fibroblast collagenase. The sequence for the tumor collagenase has two DNA base pairs which differ from the sequence of normal fibroblast c...