نتایج جستجو برای: interleukin 5

تعداد نتایج: 1299019  

Journal: :The Journal of Experimental Medicine 1990
L A Dent M Strath A L Mellor C J Sanderson

Experiments in vitro suggest that although interleukin 5 (IL-5) stimulates the late stages of eosinophil differentiation, other cytokines are required for the generation of eosinophil progenitor cells. In this study transgenic mice constitutively expressing the IL-5 gene were established using a genomic fragment of the IL-5 gene coupled to the dominant control region from the gene encoding huma...

Journal: :Expert review of clinical immunology 2016
Gilda Varricchi Giorgio W Canonica

Interleukin(IL)-9 is a pleiotropic Th2 type cytokine which has been shown to play an important role in the pathogenesis of bronchial asthma. This review will concentrate on the structure, the source, and the effects of IL-9 as well as its induction and inhibition. The signaling of IL-9 through its receptor will be outlined. Moreover the role of IL-9 in airway hyperresponsiveness, mucus overprod...

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