Summary Interleukin (IL)-33 is highly expressed in the nucleus of cells present at barrier sites and signals via ST2 receptor. IL-33 signalling essential for return to tissue homeostasis after acute inflammation, promoting fibrinogenesis wound healing injury sites. However, this wound-healing response becomes aberrant during chronic or sustained leading transforming growth factor beta (TGF-β) r...

Interleukin (IL)-33 is a member of the IL-1 family of cytokines. IL-33 is expressed in nuclei and secreted as alarmin upon cellular damage to deliver a danger signal to the surrounding cells. Previous studies showed that IL-33 is expressed in the brain and that it is involved in neuroinflammatory and neurodegenerative processes in both humans and rodents. Nevertheless, the role of IL-33 in phys...

IL-33, a member of the IL-1 cytokine family and a ligand to receptor ST2, has great potential to induce a T helper 2-type inflammatory response. IL-33 is proven to be released by epithelial cells during their injury by different environmental stimuli such as airborne allergens, viruses, and air pollutants. IL-33 acting as an endogenous danger signal is termed an alarmin. As such, this cytokine ...

Background: Fungal aeroallergens might sensitize the airway which in turn produces a specific cytokine profile. Objective: To evaluate the IL-25 and IL-33 profile in patients with fungal allergic rhinitis. Methods: The present study examined patients who were evaluated due to allergic rhinitis (AR) at Emam Reza Hospital of Shiraz, Iran. The all...

BackgroundST2 is an interleukin-1 receptor family member with membranebound (ST2L) and soluble (sST2) isoforms, and, sST2 is a biomarker for poor outcome in patients with myocardial infarction (MI). IL-33, the recently-discovered ligand for ST2, activates NF-kB and thus may regulate apoptotic cell death. We tested the hypothesis that IL-33 is cardioprotective after MI through ST2 signaling. Met...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Czarny-Działak M, Winnicka I, Działak et al. Evaluation of interleukin 33 (IL-33) levels in the course bronchial asthma (preliminary studies). Medical Studies/Studia Medyczne. 2023;39(1):26-31. doi:10.5114/ms.2023.126287. APA Czarny-Działak, M., Winnicka, I., Działak, Stanisławska, Słuszniak, A., & Cieplińska, K. ...