نتایج جستجو برای: interleukin 27

تعداد نتایج: 252167  

2014
Sanjay Swaminathan Zonghui Hu Adam W. Rupert Jeanette M. Higgins Robin L. Dewar Randy Stevens Qian Chen Catherine A. Rehm Julia A. Metcalf Michael W. Baseler H. Clifford Lane Tomozumi Imamichi

OBJECTIVE IL-27 is an immunomodulatory cytokine with potent anti-HIV properties in PBMCs, CD4+ T cells, macrophages and immature dendritic cells. Previous smaller studies have suggested that HIV-1 infection may alter IL-27 and influence HIV-1 pathogenesis. The aim of this study was to examine the relationship between plasma IL-27 levels in a well-characterised cohort of HIV-1 infected patients....

Journal: :Molecules 2016
Xiaofei Lai Hongxu Wang Ju Cao Ying Li Yubing Dai Yu Xiang Liping Zhang

Cytokines are key immunoregulatory molecules that regulate T lymphocyte-mediated immune responses and inflammatory reactions. We determined whether there is aberrant expression of interleukin-27 (IL-27) in rheumatoid arthritis (RA) patients and investigated the clinical significance of these changes. IL-27 is a key cellular factor that regulates the differentiation of CD4+ T cells, which can se...

2017
Kotaro Miura Emi Saita Norie Suzuki-Sugihara Koutaro Miyata Nobuhiro Ikemura Reiko Ohmori Yukinori Ikegami Yoshimi Kishimoto Kazuo Kondo Yukihiko Momiyama

Interleukin (IL)-27, one of cytokines in the IL-12 family, is considered to have both pro- and anti-inflammatory properties. However, blood IL-27 levels in coronary artery disease (CAD) have not been fully elucidated yet. This cross-sectional study was done to elucidate the association between blood IL-27 levels and CAD.We investigated plasma IL-27 and high-sensitivity C-reactive protein (hsCRP...

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