In this paper, we outline the main issues when designing interactive multimedia systems for children and propose a uni ed approach -acoustic, linguistic, and dialog modelingto system development. Acoustic, linguistic and dialog data collected in a Wizard of Oz experiment from 160 children ages 8-14 playing an interactive computer game are analyzed and children-speci c modeling issues are presen...

Cluster analysis is widely used for explorative data analysis, however, it is not trivial to select the right method and optimal parameters. Moreover, not all clustering methods can work with raw or dirty data. In this paper, we introduce an interactive data exploration tool, VINeM, which combines interactive mining with unsupervised tools by exploiting an intuitive neighborhood-based visualiza...

We provide the first investigation of relationship between self-awareness and dis- honesty in a multi-wave pre-registered experiment with 1,260 subjects. In wave we vary level awareness subjects' past dishonesty explore impact on behaviour tasks that include scope to lie. second degree competitiveness one our core further interactions self-awareness, (dis)honesty competition. also test for expe...

Capturing how the structures of interacting partners evolved at their binding interfaces is a fundamental issue for understanding interactomes evolution. In that scope, the InterEvol database was designed for exploring 3D structures of homologous interfaces of protein complexes. For every chain forming a complex in the protein data bank (PDB), close and remote structural interologs were identif...

Motivation Structural molecular biology depends crucially on computational techniques that compare protein three-dimensional structures and generate structural alignments (the assignment of one-to-one correspondences between subsets of amino acids based on atomic coordinates). Despite its importance, the structural alignment problem has not been formulated, much less solved, in a consistent and...

SUMMARY Genalyzer is a software tool designed for the interactive visualization of sequence matches between DNA or protein sequences. It provides visualizations on different levels of granularity, from complete overviews via zoomed regions to alignments of particular matching substrings. Genalyzer can efficiently handle very large datasets, allowing to display tens of thousands of matches betwe...

Expander2 is a flexible multi-purpose workbench for interactive term rewriting, graph transformation, theorem proving, constraint solving, flow graph analysis and other procedures that build up proofs or other rewrite sequences. Moreover, tailor-made interpreters display terms as two-dimensional structures ranging from trees and rooted graphs to a variety of pictorial representations that inclu...

OWEN is an interactive tool for aligning two long DNA sequences that represents similarity between them by a chain of collinear local similarities. OWEN employs several methods for constructing and editing local similarities and for resolving conflicts between them. Alignments of sequences of lengths over 10(6) can often be produced in minutes. OWEN requires memory below 20 L, where L is the su...

This study compares the handling of agreement and disagreement by speakers from two different cultural groups: London’s British West African community and its mainstream British white community. Using data from elicited conversations, we consider naturally-occurring agreements and disagreements at three different linguistic levels. Firstly, based on Pomerantz’s (1984) observations of turn-takin...