Bisphenol S is an endocrine disruptor exhibiting metabolic disturbances, especially following perinatal exposures. To date, no data are available on the obesogen effects of BPS in a mutligenerational issue. We investigated multigenerational study by focusing body weight, adipose tissue and plasma parameters male female mice. Pregnant C57BL6/J mice were exposed to (1.5 ?g/kg bw/day ie human equi...

Insulin-like growth factor I (IGF-I) is a polypeptide hormone secreted by multiple tissues in response to growth hormone (GH). It is partly responsible for GH activity, and also has glucose-lowering and anabolizing effects. Ninety percent of circulating IGF-I originates in the liver and has autocrine, paracrine, and endocrine effects, the latter on multiple tissues. Liver cirrhosis results in a...

Toutes les proteines et tout le lactose, et environ 50% des acides gras des lipides du lait sont synthdtisks par les cellules CpithCliales de la gland mammaire. Au pic de la lactation, il y a une demande CnergCtique ClevCe auprbs de ces cellules pour fournir les substrats circulants (glucose, acides gras, corps cCtoniques, triacylglycCrols et acides aminks), pour les rCactions de biosynthbse, e...

abstract: introduction & objective: there are different methods for improving hypercholesterolemia, insulin resistance and hypertriglyceridemia, the major risk factors of cardio-vascular disease. calcium, a nutrient essential for many vital functions of the body is now receiving much attention for its possible hypolipidemic effects. the large bodies of studies on the effects of calcium on the s...

Les polyendocrinopathies auto-immunes (PEAI) designent lapparition de deux ou plusieurs atteintes endocrines auto-immunes, associees non a dautres maladies endocrines. Le diabete type 1 saccompagne dune frequence elevee auto-immunes. Lobjectif notre travail est determiner les differents aspects epidemiologiques, cliniques, immunologiques, therapeutiques des autoimmunes au cours du et danalyser ...

The biochemical and hormonal data in patients with adrenal incidentalomas were evaluated to compare the differences between adrenal adenomas and other benign lesions and to find the relationship between metabolic parameters and adrenal hormones. Ninety two patients (29men, age 20-90 years) with incidentally discovered unilateral or bilateral adrenal masses detected on CT were included in this s...