Background: The thyroid gland secrete the hormone thyroxin (T4) and triiodothyronine (T3). They have a profound effect on the metabolism of hormones. The aim of this study was to servey the effect of the extract of plant root barberry on the amount of thyroid hormone in rat having hypercholesterolemia. Materials and Methods: In this experimental study, 40 Wistar rats were divided into 5 groups ...

  Objective(s):In insulin resistance, the insulin action in liver, muscles and adipocytes decreases and result in hyperglycemia, dyslipidemia and hyperinsulinemia. In this study we evaluate the effect of Zataria multiflora extract on insulin sensitivity in high fructose fed insulin resistant rats, since this extract was shown antihyperglycemic effect in streptozotocin induced diabetes in rats. ...

objectives insulin resistance has been considered as the most important component of type 2 diabetes mellitus (dm2). plants used in folk medicine to treat diabetes mellitus represent a viable alternative for the control of this disease. this study was aimed to examine the antidiabetic effects of three iranian medicinal plants i.e. urtica dioica, trigonella foenum-graecum and fumaria officinalis...

background: several herbal remedies are used in traditional medicine for treatment of liver disorders, but their efficacy, safety, and dosage have not been investigated so far. objective: the present study was aimed to evaluate the liver protective effects of medicinal herbs extracts such as cynara scolymus leave (artichok), cichorium intybus roots (chichory), taraxacum officinale root (dandeli...

AIM Food and medicinal applications of barberry date back to 2500 years ago. This study investigates Berberis integerrima impact on lymphocytic immune responses. MATERIALS & METHODS Balb/c splenocytes were treated by 0.001-1000 μg/ml of B. integerrimaaqueous and alcoholic extracts in presence of phytohemagglutinin and lipopolysaccharide mitogens. Cell proliferation was assayed and cytokines w...

Background: Insulin resistance plays a key role in the onset of several metabolic disorders. Aim and Objectives: To determine the insulin sensitizing property of aqueous extract of Gymnema sylvestre leaves on dexamethasone induced insulin resistance in rats. Materials and Methods: Animals were divided into five groups (n=6) and the study was conducted for a period of 12 days. Insulin resistance...

Andrographis paniculata ethanolic extract was evaluated to screen the effect on insulin resistance using a combination of fat-fed diet and low dose streptozotocin. The glucose-insulin index as a measure of insulin action on glucose disposal rate was calculated during the intraperitoneal glucose tolerance test. Oral administration of 1000 mg/kg extract to rats was able to cause a significant (p<...

possessing putative hypolipidemic effects, teucrium polium (tp) have been traditionally used as a medicinal plant in iran. the aim of the present study was to investigate this effect on the sucrose-induced insulin resistance male rat model. thirty wistar male rats weighting 180 ± 20 g were divided into five groups of six each. four groups were given sucrose 50% in drinking water for 10 weeks. i...

This study investigated whether decaffeinated green coffee bean extract prevents obesity and improves insulin resistance and elucidated its mechanism of action. Male C57BL/6N mice (N = 48) were divided into six dietary groups: chow diet, HFD, HFD-supplemented with 0.1%, 0.3%, and 0.9% decaffeinated green coffee bean extract, and 0.15% 5-caffeoylquinic acid. Based on the reduction in HFD-induced...

background: “teucrium polium l.” (tp) has been long recommended in iranian folk medicine for its anti-diabetic activities. we attempt here to evaluate the effect of tp extract on insulin secretion in rat pancreas. methods: rat pancreas was isolated in situ and perfused with krebs solution containing low glucose (lg, 2.8 mm) or high glucose (hg, 16.7 mm) as perfusate. the aqueous extract (aq. e)...