Gamma-Ray Bursts (GRBs) are unique probes of the cosmic star formation history and the state of the intergalactic medium up to the redshifts of the first stars. In particular, the ongoing Swift mission might be the first observatory to detect individual Population III stars, provided that the massive, metal-free stars were able to trigger GRBs. Swift will empirically constrain the redshift at w...

Motivation: Assessing the enrichment of biological pathways is a critical problem in systems biology, which has received much attention in recent years. However, available methods often make simplifying assumptions about correlations among components of pathways, and/or rely on appropriate choices of input parameters and sizes of gene sets. In addition, current methods often focus on analysis o...

Epigenomics is crucial to understand biological mechanisms beyond genome DNA. To better represent epigenomic knowledge and support data integration, we developed a prototype Epigenome Ontology (EGO). EGO top level hierarchy and design pattern are provided with a use case illustration. EGO is proposed to be used for statistically analyzing enriched epigenomic features based on given sequence dat...

The paper describes the process and new methodology of a hybrid prediction system for business sequential data i.e. debt portfolio appraisal. Conducting the local area competence data mining approach, repayment values are predicted by means of combination of various data mining techniques. The methods include clustering of references, model selection and enrichment of input variables with predi...

Description This package generates ranked lists of differential gene expression for either disease or drug profiles. Input data can be downloaded from Array Express or GEO, or from local CEL files. Ranked lists of differential expression and associated p-values are calculated using Limma. Enrichment scores (Subramanian et al. PNAS 2005) are calculated to a reference set of default drug or disea...

This paper presents a demonstration of a stochastic prosody tool for enrichment of synthesized speech using SSML prosody tags applied over hierarchical thematicity spans in the context of a CTS application. The motivation for using hierarchical thematicity is exemplified, together with the capabilities of the module to generate a variety of SSML prosody tags within a controlled range of values ...

Description This package generates ranked lists of differential gene expression for either disease or drug profiles. Input data can be downloaded from Array Express or GEO, or from local CEL files. Ranked lists of differential expression and associated p-values are calculated using Limma. Enrichment scores (Subramanian et al. PNAS 2005) are calculated to a reference set of default drug or disea...

Description This package generates ranked lists of differential gene expression for either disease or drug profiles. Input data can be downloaded from Array Express or GEO, or from local CEL files. Ranked lists of differential expression and associated p-values are calculated using Limma. Enrichment scores (Subramanian et al. PNAS 2005) are calculated to a reference set of default drug or disea...

The highly elevated concentrations of the rare earth elements and yttrium (REY), U, Mo, Se, Pb in late Permian coals some coalfields Guangxi Province, South China, have been widely investigated; however, mode occurrence enrichment mechanism these critical are still under debate. This study investigates mineralogical geochemical compositions non-coal rocks from Xian’an Coalfield Province to disc...

Soils contain the largest pool of terrestrial organic carbon (C) and are a major source of atmospheric carbon dioxide (CO2). Thus, they may play a key role in modulating climate change. Rising atmospheric CO2 is expected to stimulate plant growth and soil C input but may also alter microbial decomposition. The combined effect of these responses on long-term C storage is unclear. Combining meta-...