نتایج جستجو برای: inotropic
تعداد نتایج: 5240 فیلتر نتایج به سال:
A 67-years old woman with no cardiac past history was presented postoperatively after elective surgery for pertrochanteric femur fracture with dyspnea, hypotension, pulmonary congestion, oliguria and tachycardia. Cardiogenic shock was suspected and she was transferred to the Coronary Care Unit (CCU) and treated as such with diuretic and an inotropic agent. No improvement occurred and her condit...
BACKGROUND Left ventricular dysfunction is common after coronary artery bypass graft and valve replacement surgeries and is often treated with inotropic drugs to maintain adequate hemodynamic status. In this study, we aimed to identify the demographic, clinical, laboratory, echocardiographic and hemodynamic factors that are associated with use of inotropic drugs in patients undergoing concomita...
Faucher FA, Gannier FE, Lignon JM, Cosnay P, Malécot CO. Roles of PKA, PI3K, and cPLA2 in the NO-mediated negative inotropic effect of 2-adrenoceptor agonists in guinea pig right papillary muscles. Am J Physiol Cell Physiol 294: C106–C117, 2008. First published October 17, 2007; doi:10.1152/ajpcell.00231.2007.— Although 2-adrenoceptors represent 15–25% of -adrenoceptors in the guinea pig heart,...
Pharmacological examinations of isolated auricles from Sepia officinalis were carried out to analyze the putative role of the monoaminergic transmitter/receptor system in the control of auricle function. In conjunction with histofluorescence studies and HPLC analyses, evidence of a double excitatory serotonergic and noradrenergic innervation of the auricles was obtained. Serotonin-induced posit...
BACKGROUND Adenosine attenuates beta-adrenoceptor-mediated inotropic responses through GTP-binding protein in vitro. The goal of the present study was to test the hypothesis that endogenous adenosine released from the ischemic myocardium blunts the inotropic response to beta-adrenergic stimulation. METHODS AND RESULTS In 45 open-chest dogs, the left anterior descending coronary artery was per...
Both bethanechol and physostigmine produced dose-dependent negative chrono-, dromo- and inotropic effects in the dog isolated atrial preparation. Within a relatively small dose of bethanechol and physostigmine, negative inotropic effect was clearly induced but no significant chrono- and dromotropic changes were observed. With a relatively large dose, the two cholinomimetics caused negative chro...
The administration of single large doses of angiotensin II has been shown to elicit positive chronotropic and inotropic effects in isolated heart preparations."' Continuous infusions of this hormone in normotensive animals, however, in amounts sufficient to produce marked vasoconstrictor responses, elicit only infrequent and transient increases of contractility.! Occasionally, negative inotropi...
Michael J. Antonaccio and Benedict R. Lucchesi Department of Pharmacology, The University of Michigan Medical School, Ann Arbor, Michigan 48104 (Received 22 May 1970 ; in final form 3 August 1970) Glucagon has been shown to be both a positive inotropic and chronotropic agent in many species including man (1-5). However, the positive inotropic effect of glucagon on dog papillary muscles can be r...
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