نتایج جستجو برای: innate immune response
تعداد نتایج: 1154602 فیلتر نتایج به سال:
Adenovirus is a nonenveloped dsDNA virus that activates intracellular innate immune pathways. In vivo, adenovirus-immunized mice displayed an enhanced innate immune response and diminished virus-mediated gene delivery following challenge with the adenovirus vector AdLacZ suggesting that antiviral Abs modulate viral interactions with innate immune cells. Under naive serum conditions in vitro, ad...
Timothy Billiar summarizes the role of the innate immune response in the clinical course following severe injury and envisions a field of "trauma immunology."
Many pathogens that can infect C. elegans have been described, including some that co-exist with the nematode in its natural environment. This chapter describes our current understanding of the different innate immune responses of C. elegans that follow infection. It focuses on the main signalling pathways that have been identified and highlights the inclusion of certain molecular cassettes in ...
The innate immune response is primarily mediated by the Toll-like receptors functioning through the MyD88-dependent and TRIF-dependent pathways. Despite being widely studied, it is not yet completely understood and systems-level analyses have been lacking. In this study, we identified a high-probability network of genes activated during the innate immune response using a novel approach to analy...
The first year of life represents a time of marked susceptibility to infections; this is particularly true for regions in sub-Saharan Africa. As innate immunity directs the adaptive immune response, the observed increased risk for infection as well as a suboptimal response to vaccination in early life may be due to less effective innate immune function. In this study, we followed a longitudinal...
The innate immune response is evoked as a consequence of interactions between invading foreign infectious agents and host immune cells. A successful innate immune response is pivotal in maintaining the delicate balance between health and disease; an insufficient response results in infection, whereas an excessive response results in prolonged inflammation and tissue damage. Alterations in the s...
The nuclear receptor superfamily consists of the steroid and non-steroid hormone receptors and the orphan nuclear receptors. Small heterodimer partner (SHP) is an orphan family nuclear receptor that plays an essential role in the regulation of glucose and cholesterol metabolism. Recent studies reported a previously unidentified role for SHP in the regulation of innate immunity and inflammation....
Background and purpose: Ïn recent years, different studies have been performed regarding the influence of magnetic field on the immune system. There are many contraversies about the effects of different frequencies and amplitudes on the immune system. Materials and methods : Ïn this experimental study, the effects of different frequencies of magnetic field (0,5,50,500 and 5000 Hz) have bee...
Innate immunity is the first line of defense against infectious microorganisms. The innate immune system relies on germ line-encoded pattern recognition receptors (PRRs) to recognize pathogen-derived substances (Janeway 1989). Activation of the innate immune system through these receptors leads to the expression of a vast array of antimicrobial effector molecules that attack microorganisms at m...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید