SRC kinases and PKR are intracellular protein kinases, which play key roles in intracellular viral replication. In this research, the effect of SRC kinase inhibition and PKR activation and inhibition on replication of coxsakievirus (CVB3), an entrovirus of the family picornaviridae – causative agents of fatal myocarditis, was studied. Vero and Hela cells were cultured and infected with CVB3 in ...

the effect of cocl2 as an ethylene synthesis inhibitor on changes of protein pattern was investigated in potato (solanum tuberosum l.) plants cultivar white desiree. in vitro grown plants were subjected to ms medium containing 0, 5, 10, 15, 20, 30, 40 and 60 mg/l cocl2 for 4 weeks. different concentrations of cocl2 showed significant effect on the total soluble proteins. among different concent...

The human protein kinase ULK3 regulates the timing of membrane abscission, thus being involved in exosome budding and cytokinesis. Herein, we present first high-resolution structures domain. Its unique features are explored against background other ULK kinases. An inhibitor fingerprint indicates that is highly druggable capable adopting a wide range conformations. In accordance with this, descr...

SRC kinases and PKR are intracellular protein kinases, which play key roles in intracellular viral replication. In this research, the effect of SRC kinase inhibition and PKR activation and inhibition on replication of coxsakievirus (CVB3), an entrovirus of the family picornaviridae – causative agents of fatal myocarditis, was studied. Vero and Hela cells were cultured and infected with CVB3 in ...