Background and objective: Peel oil and juice of citrus fruits have furocoumarin (Psoralen) that can induce phytophotodermatitis. If the reaction is mild, then only hyperpigmentation (Without itching, burning, erythema, vesicle and bullae, formation) may occur. The objective of this study was to describe the patients with hyperpigmentation of back of the hands. Materials and Methods: Thirty-two ...

Gingival hyperpigmentation is mostly caused by the physiologic deposition of melanin by melanocytes. Melanin pigmentation of the gingiva is completely benign and does not present a medical problem. In "Gummy Smile" Patients, melanin gingival hyperpigmentation causes an esthetic problem and physiologic disturbances. Many methods are now available for depigmentation of the gingival. This paper re...

conclusions all plants could inhibit mushroom tyrosinase, but more investigations on human tyrosinase and clinical studies are needed. results the hydroalcoholic extract of p. alkekengi showed the most tyrosinase inhibitory effect with ic50 of 0.09 mg/ml vs. 0.38, 0.38 and 2.82 mg/ml of b. persicum, a. rosea and m. vulgare, respectively. m. vulgare exhibited uncompetitive inhibition and other p...

Objective: To assess the efficacy and safety of IPL in patients with inflammatory Acne Vulgaris.
 Study Design: Quasi-experimental study.
 Place Duration Study: Department Dermatology, Pakistan Air Force Hospital, Fazaia Medical College, Islamabad Pakistan, from Aug 2019 to Jan 2020.
 Methodology: Ninety facial acne were enrolled received four Intense Pulsed Light (IPL) sessions ...

CARP: confluent and reticulated papillomatosis PP: prurigo pigmentosa INTRODUCTION Prurigo pigmentosa (PP) is an uncommon, acquired inflammatory disorder with a predilection for young adults of Asian descent. This condition is manifested by highly pruritic, reticulated, and erythematous papules that resolve with hyperpigmentation. Multiple cases of PP have been reported since its initial descri...

linear and whorled nevoid hypermelanosis. J Eur Acad Dermatol Venereol. 2005;19:638--9. 4. Cho E, Cho SH, Lee JD. Progressive cribriform and zosteriform hyperpigmentation: a clinicopathologic study. Int J Dermatol. 2012;51:399--405. 5. Iijima S, Naito Y, Naito S, Uyeno K. Reticulate hyperpigmentation distributed in a zosteriform fashion: a new clinical type of hyperpigmentation. Br J Dermatol. ...

The development of blue or gray cutaneous hyperpigmentation is a rare complication of chronic imipramine therapy. Treatment options for imipramine-induced hyperpigmentation are limited but include topical retinoids, bleaching agents, and laser therapy, with varying degrees of success. We report a case in which Q-switched alexandrite laser therapy alone led to nearly complete resolution of imipr...