The development of Insulin resistance in obesity is associated with infiltration of immune cells in white adipose tissue (WAT). Especially macrophage infiltration in WAT is known to produce several proinflmmatory cytokines which induces the state of inflammation and impairs the insulin signaling and related pathways. Several animal and human studies have been conducted to unravel the mystery of...

purpose the inflammatory state of adipose tissue in obese subjects may be the most important factor linking increased adipose tissue mass to insulin resistance. chemerin is a newly discovered adipokine that plays an important role in macrophage infiltration into adipose tissue and may contribute to the development of inflammation and insulin resistance. we examined the effects of 12 weeks of ae...

The cathode materials fabrication with outstanding performance and stability at intermediate temperatures of 600–800℃ is required for the prospective mass production solid oxide fuel cells (SOFCs). Infiltration a potential method because it has proven successful in cell enhancement. This study mainly focuses on electrical conductivity long-term reliability symmetric NdBa0.5Sr0.5Co2O5+δ (NBSC) f...

Extensive infiltration of the surrounding healthy brain tissue is a cardinal feature of glioblastomas, highly lethal brain tumors. Deep infiltration by the glioblastoma cells renders complete surgical excision difficult and contemporary adjuvant therapies have had little impact on long-term survival. Thus, deep infiltration and resistance to irradiation and chemotherapy remain a major cause of ...

the aim of the present study was to investigate the effects of anabolic steroid stanozolol along with eight weeks of resistance training on structural changes in male rats' liver tissue. for this purpose, 28 male adult wistar rats (age: 12 weeks old and 228.53±7.94 g body weight) were randomly assigned to four groups: group 1: control+placebo (n=7), group 2: resistance training+placebo (n=...

Chronic low-grade inflammation is an important contributor to the development of insulin resistance, a hallmark of type 2 diabetes mellitus (T2DM). Obesity and high-fat feeding lead to infiltration of immune cells into metabolic tissues, promoting inflammation and insulin resistance. We hypothesized that macrophages from mice lacking NOX2 (Cybb), an essential component of the NADPH oxidase comp...

Ticks are ectoparasitic arthropods that can transmit a variety of microorganisms to humans and animals during blood feeding, causing serious infectious disorders, including Lyme disease. Acaricides are pharmacologic agents that kill ticks. The emergence of acaricide-resistant ticks calls for alternative control strategies for ticks and tick-borne diseases. Many animals develop resistance to tic...

OBJECTIVE To evaluate the influence of treatment with different doses of methylprednisolone on the mechanical resistance and possible histological alterations of the rotator cuff tendon in rats. METHODS Male Wistar rats were divided randomly into four treatment groups: sham, vehicle or 0.6 mg/kg or 6.0 mg/kg of methylprednisolone. Changes to mechanical resistance (in N) and histological param...

Increased mucin expression is a feature of nasal polyposis. Corticosteroids reduce polyp size and symptoms, but their effect on mucin production remains unknown. In this study, the effects of intranasal corticosteroids on MUC5AC mucin expression, nasal resistance, eosinophil and neutrophil infiltration, epidermal growth factor receptor (EGFR), interleukin (IL)-8, and tumour necrosis factor (TNF...

Though it is vital to estimate infiltration as one of the key factors in effective management of water resources, only few studies have been carried out either to determine the infiltration or to compare the performance of infiltration models for coarse textured soils. Thus, the present study was conducted to accomplish two objectives. First to estimate the Horton’s infiltration model parameter...