Indonesia sebagai negara maritim yang memiliki sumber daya ikan melimpa namun tidak lepas dari berbagai infeksi jenis virus. Infeksi virus pada menyebabkan kematian akibat kerusakan multiorgan seperti nekrosis dan perdarahan. Kematian mengakibatkan kerugian ekonomi bagi para pembudidaya ikan. Kurangnya pengetahuan tentang penyakit pencehahannya menjadi salah satu faktor tingginya kasus Tulisan ...

Infectious pancreatic necrosis (IPN) virus has been purified and some physicochemical properties of its nucleic acid and protein moieties have been determined. The buoyant density of the virus particle in CsC1 is 1.35 g/ml; degraded particle banded at a density of 1.31 g/ml. The virus nucleic acid was found to be doublestranded, according to several different criteria, namely resistance to panc...

An electron microscopical and biochemical examination of the properties of infectious pancreatic necrosis virus (IPN) and of its ribonucleic acid (RNA) was made. The buoyant density of IPN in CsCl was found to be 1.33 g/cm(3). Electron microscopical examination of the banded virus revealed structures similar in size (74 nm) and shape to reoviruses but lacking a characteristic inner capsid struc...

We developed a reverse genetics system for infectious pancreatic necrosis virus (IPNV), a prototype virus of the Birnaviridae family, with the use of plus-stranded RNA transcripts derived from cloned cDNA. Full-length cDNA clones of the IPNV genome that contained the entire coding and noncoding regions of RNA segments A and B were constructed. Segment A encodes a 106-kDa precursor protein which...

Infectious Pancreatic Necrosis Virus (IPNV) is a member of the family Birnaviridae that has been linked to high mortalities in salmonids. Bacterial based systems as live vectors for the delivery of heterologous antigens offer a number of advantages as vaccination strategies. VP2 is a structural viral protein of IPNV with immunogenicity effects. In this study IPNV was isolated from diseased fry ...

Infectious pancreatic necrosis virus (IPNV) is the causative agent of infectious pancreatic necrosis (IPN) disease in salmonid fish. Recent studies have revealed variation in virulence between isolates of the Sp serotype, associated with certain residues of the structural protein VP2. The isolates are also highly heterogenic in the coding region of the nonstructural VP5 protein. To study the in...