Pigs are evidently more resistant to avian than swine influenza A viruses, mediated in part through frontline epithelial cells and alveolar macrophages (AM). Although porcine AM (PAM) are crucial in influenza virus control, their mode of control is unclear. To gain insight into the possible role of PAM in the mediation of avian influenza virus resistance, we compared the host effects and replic...

In 2008, 800 adults living within rural Kampong Cham Province, Cambodia were enrolled in a prospective cohort study of zoonotic influenza transmission. After enrollment, participants were contacted weekly for 24 months to identify acute influenza-like illnesses (ILI). Follow-up sera were collected at 12 and 24 months. A transmission substudy was also conducted among the family contacts of cohor...

Avian influenza viruses circulate widely in birds, with occasional human infections. Poultry-exposed individuals are considered to be at high risk of infection with avian influenza viruses due to frequent exposure to poultry. Some avian H7 viruses have occasionally been found to infect humans. Seroprevalence of neutralizing antibodies against influenza A/H7N7 virus among poultry-exposed and une...

Infectious bronchitis, Newcastle disease, infectious laryngotracheitis, avian influenza, and pneumovirus are the viruses that more frequently affect the respiratory tract of chickens, because of their tendency to change its antigenic properties Infectious laryngotracheitis has appeared in the broiler industry as a serious disease. Newcastle is a highly contagious, disease in which all birds in ...

Accumulating infections of highly pathogenic H5N1 avian influenza in humans underlines the need to track the ability of these viruses to spread among humans. A human-transmissible avian influenza virus is expected to cause clusters of infections in humans living in close contact. Therefore, epidemiological analysis of infection clusters in human households is of key importance. Infection cluste...

Avian influenza is caused by influenza viruses such as the influenza A virus. In 1997 in Hong Kong, the avian influenza viruses were found to cross the species barrier to infect human beings and cause respiratory illness and death. H5N1 viruses later reemerged in Asia with human cases of infection, of which more than 50% were fatal. We proposed to genetically engineer naturally occurring bacter...

Avian influenza virus (AIV) infection is a major cause of bird or human mortality and morbidity, therefore the rapid identification of the virus is of important clinical and epidemiological implication. Methods: A multiplex Reverse Transcriptase PCR (RT-PCR) was optimized for the detection of influenza A virus and the H5 and H9 subtypes. The influenza type A specific primers were directed to t...

BACKGROUND Influenza virus poses serious threats to human health, especially human infection with avian influenza virus. Laggera pterodonta (DC.) Benth is a medicinal plant that is widely used in Traditional Chinese Medicine, especially in Yunnan province, and has been used to treat influenza, pharyngolaryngitis, and bronchitis. However, the compound(s) responsible for the activity and their me...

on june 2005, a respiratory disease was observed in the chickens of a large broiler farm in kermanshahprovince, west of iran. relatively severe respiratory signs started with sneezing at 27 days of age. thedisease lasted up to the end of fattening period and accompanied by increased mortality (13.6%). at postmortemexamination, tracheitis, airsacculitis and pneumonia were obvious. serologic exam...