In the sector of biopharmaceuticals, the dominant business model remains the one of big pharmas: the vertical integration. However we currently observe in the European biotechnology industry the emergence of new business models. This article studies in particular the cases of an orchestra firm and a repurposing firm, both virtual all along the value chain of drugs. It shows that being virtual i...

Nowadays, industrials are seeking for models and methods that are not only able to provide efficient overall production performance, but also for reactive systems facing a growing set of unpredicted events. One important research activity in that field focuses on holonic/multi-agent control systems that couple predictive/proactive and reactive mechanisms into agents/holons. Meanwhile, not enoug...

This study investigates the impact of COVID-19 pandemic on daily stock returns in Kuwait Stock Market (KSE) over period from 28 March to 20 April 2020. By applying event methodology (ESM) approach, results reveal that has positively impacted stocks banks, consumer goods and telecommunications sectors. However, oil & gas, real estate, financial, basic materials, industrials, services, in...

Staff Reporters of THE WALL STREET JOURNAL After Friday's 30-point swoon in the Dow Jones Industrial Average, it's time for a stock market checkup . The market ran hard and high for six weeks. And there isn't any reason to think there aren't more gains ahead this year and maybe next year, many analysts say . But just as you don't keeping tooling down the highway in your car without occasionally...

ABSTRACT This special issue of INSIGHT highlights the ninth edition French Systems Engineering Academia‐Industry meetings, organized by AFIS (Association Française d'Ingénierie Système), chapter INCOSE, and supported universities as a regular series, usually every two years. Due to COVID‐19 crisis, this occurred virtually in December 2020. These which are composed workshops plenary lectures, pr...

Multivariate Discriminant Analysis (MDA) has long been used to classify failing and non-failing firms with high accuracy rates, although a number of methodological flaws are well known. The alternative approach based on Conditional Probability Analysis (CPA) models have been applied to forecast mergers and acquisitions and extended to the prediction of corporate failure. This is used her to dis...

In the field of structural health monitoring or machine condition monitoring, the activation of nonlinear dynamic behavior complicates the procedure of damage or fault detection. Blind source separation (BSS) techniques are known as efficient methods for damage diagnosis. However, most of BSS techniques repose on the assumption of the linearity of the system and the need of many sensors. This a...

Production of exopolysaccharides (EPSs) has been reported in prokaryotes and eukaryotes. Microbial have increased interest as another category microbial products utilized the pharmaceutical, biomedical, food industries. Investigators are considering replacing synthetic stabilizers with organic ones by investigating EPS fermentation-based dairy Particularly for enhancement rheology fermented ite...

A Moroccan bentonite was activated by sodium carbonate (Na–Be), and a combined chemical thermal activation (Na–Be450). The materials characterization performed XRD, EDS, FTIR, SEM porosity measurements. efficiency of Na–Be Na–Be450 as low-cost adsorbents to remove nickel silver from aqueous solution checked. Langmuir, Freundlich Langmuir-Freundlich models were used for the analysis equilibrium ...

Open-source devices are widespread and have been available to everyone over the past decade. The low cost of such boosts creation instruments for various applications as smart farming, environmental monitoring, animal behavior human health etc. This research aims use statistical methods assess agreement similarity in order compare an open-source weather station that was constructed programmed f...