نتایج جستجو برای: inducing ligand
تعداد نتایج: 169340 فیلتر نتایج به سال:
Atopic dermatitis is a major allergic disease that develops through dysregulation of Th2-mediated inflammation. Although dendritic cells (DCs) have been thought to play a critical role in the upstream phase of the allergic cascade, conventional drugs such as steroids and chemical mediator antagonists target the effector cells or factors in allergic inflammation. Recently, it has been demonstrat...
IgA nephropathy (IgAN) is the most common primary glomerulonephritis globally, with up to 45% of IgAN patients at risk progressing ESKD. There are currently no approved treatments specifically for nephropathy. The initiating step in pathogenesis excess production galactose-deficient IgA1 (Gd-IgA1) resulting formation pathogenic immune complexes that cause kidney inflammation and damage. A Proli...
Tumor necrosis-factor related apoptosis-inducing ligand, also known as TRAIL or APO2L (Apo-2 ligand), is a cytokine of the TNF superfamily acknowledged for its ability to trigger selective apoptosis in tumor cells while being relatively safe towards normal cells. Its binding to its cognate agonist receptors, namely death receptor 4 (DR4) and/or DR5, can induce the formation of a membrane-bound ...
By their conformational flexibility, Möbius aromatic hexaphyrins provide a dynamic chirality attractive to develop stimuli responsive systems such as chiroptical switches. A regular [28]hexaphyrin has been equipped with chiral coordinating arm achieve transfer of from fix stereogenic element the one. The allows straightforward formation labile monometallic ZnII complexes an exogenous ligand, ei...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید