This article deals with heparin-induced thrombocytopenia. It discusses the pathophysiology of the disease, as well as the diagnostic challenges and therapeutic management. The incidence of the disease and screening recommendations are reviewed. The article also emphasizes the importance of correct diagnosis and treatment options. This article is intended for surgeons in all specialties and leve...

Heparin-induced thrombocytopenia can be a serious and difficult-to-diagnose complication of heparin therapy. Serum from patients with heparin-induced thrombocytopenia can cause heparin-dependent platelet aggregation, but the low sensitivity and specificity of this test limit its clinical usefulness. In this report we describe an assay for heparin-induced thrombocytopenia that is both sensitive ...

Heparin-induced thrombocytopenia (HIT) is the most important and most frequent drug-induced, immune-mediated type of thrombocytopenia. It is associated with significant morbidity and mortality if unrecognized. In this review, we briefly discuss the main features of heparin-induced thrombocytopenia, particularly analyzing the most recent advances in the pathophysiology, diagnosis and treatment o...