Postherpetic neuralgia is a well-studied and somewhat common sequala of herpes zoster leading to intense pain episodes. Pain-induced vasovagal episodes can rarely lead asystole, which fatal potential complication. It crucial have high clinical suspicion asystole when patient presents with severe herpetic syncope. This unique cause 67-year-old Caucasian female who presented syncope caused by pos...

Introduction: 17β-Estradiol is a neuroactive steroid and its pain modulatory role has been well studied previously. 17β-Estradiol modulates nociception by binding to its receptors and also by allosteric interaction with other membrane - bound receptors such as glutamate and GABAA receptors. Paragigantocellularis lateralis (LPGi) is also involved in pain modulation and perception, in addition...

conclusions nitroglycerine may be a safe and effective adjuvant therapeutic for pain reduction in patients under propofol injection. hence, its use for reduction of propofol injection-induced pain is recommended. results the pain severity in nitroglycerine group was significantly lower compared with the placebo group (p < 0.0001). moreover, the local adverse reactions were observed only in thre...

introduction: we investigated the role of atp-sensitive potassium channels and l-type calcium channels in morphine-induced hyperalgesia after nociceptive sensitization. methods: we used a hotplate apparatus to assess pain behavior in male nmri mice. nociceptive sensitization was induced by three days injection of morphine and five days of drug free. on day 9 of the schedule, pain behavior test ...

  In this study, the effects of lead acetate on two types of pain (nociception and inflammation) induced by formalin and its interaction with the opioid system and morphine-induced analgesia were examined. Male albino mice weighing 22-27 g were used in the experiments. Morphine was administered subcutaneously 30 minutes before formalin injection. Lead acetate was intraperitoneally administered ...

introduction: it is known that acute and chronic stress induce hormonal and neuronal changes which affecting both pain threshold and nociceptive behaviours. orexin plays an important role in modulation of pain and stress. considering pain modulation during stress and the role of orexin in pain and stress, orexin might be involved in pain modulation during stress.we evaluated the involvement of ...