Eggplant is a vegetable crop with high economic value that cultivated worldwide. The dwarf mutant an important germplasm material has been extensively used in breeding. However, no eggplant mutants have reported, and little known regarding the genes responsible for dwarfism eggplant. In this study, we isolated (dwf) from ethyl methyl sulfonate (EMS)-induced library. Genetic analysis revealed dw...

background recently, several reports issued clevudine induced myopathy in the long term use. objectives the aim of this study was to investigate antiviral effects and adverse events of clevudine monotherapy in patients with chronic hepatitis b (chb). patients and methods the subjects were 110 treatment-naïve chb patients. they were treated with 30 mg clevudine/day for more than six months. viro...

Selection-induced mutations are nonrandom mutations that occur as specific and direct responses to environmental challenge. Examples of selection-induced mutations have been reported both in bacteria and in yeast. I previously showed (Hall 1988) that excisions of the mobile genetic element IS150 from within bglF are selection induced and argued that they occurred because they were potentially a...

Although pollen viability promises to be a very sensitive indicator of environmental mutagenesis, its utility in this regard is confounded by the fact that it is influenced also by nonmutagenic environmental stress. However, with appropriately homozygous material, we may discriminate between mutagenic and nonmutagenic influences on pollen viability. Pollen inviability resulting from mutagenesis...

In an attempt to determine the possible role of Ku-dependent end joining in mutagenesis resulting from DNA double-strand breaks, mutations induced by bleomycin at the hprt locus in plateau phase normal CHO-K1 and Ku-deficient xrs-6 cells were examined. Plateau phase xrs-6 cells were 500-fold more sensitive to chronic bleomycin treatment than were CHO-K1 cells. XRCC4-deficient XR-1 cells were ap...