objectivethis study was initiated to investigate the effect of portulaca oleraceae on morphine dependence in mice.materials and methodsdependence was induced using the subcutaneous injections of morphine for 3 days. on the day 4, morphineinjected 2 h prior to intraperitoneal injection of naloxone. the plant extracts ethanolic or aqueousadministered 0.5 h before the final dose of morphine. the n...

ôbjective: ço-morbidity of personality disorders with illicit drug abuse has a deleterious effect on the management outcome of both conditions. this study was conducted to assess the prevalence of different personality disorders among substance dependent patients in an ïranian city (ïsfahan) with a view to have a better understanding of various management strategies. methods: â total of 368 dif...

conclusions zolpidem dependency and withdrawal seizure can occur with a dosage under last reported doses. therefore, possibility of mentioned problems cannot be excluded at any dosage and physicians should pay more attention to potential of zolpidem to create these adverse effects. introduction zolpidem is a short acting inducer of sleep and thought to lack benzodiazepine properties such as anx...

repetitive transcranial magnetic stimulation (rtms) has been used widely in various psychiatric disorders like depression and schizophrenia. there have been some reports of its usefulness in alcohol dependence and substance use disorders. the present paper reviews the studies done using rtms in substance use disorders including alcohol and nicotine dependence. various studies done have been rev...

Background: Many psychiatric patients have nicotine and other substance dependence. Objective: To determine the prevalence of nicotine and opium dependence among psychiatric in-patients inKerman, a city in southwesternIran. Methods: Three groups of psychiatric inpatients, chronic medical patients and a sample from local population, each including 400 subjects were selected.  Nicotine dependence...

conclusions the significant difference between groups 1 and 3 permits to establish a correlation between degree of nicotine addiction and hearing loss. however, further studies are needed to identify the mechanisms leading to hearing loss. patients and methods the study recruited smokers (100) and non-smokers as a reference group (100) aged 21 to 50 years living in noisy or quiet areas of beiru...

a recent study indicates that the incidence of smoking cessation varies with age. although nicotine dependence (nd) has been regarded as one of the most significant barriers of successful smoking cessation, few researches have focused on the relationship between nicotine dependence and age.a cross-sectional study (conducted in 2013) with 596 chinese rural male current smokers was performed to s...

objectives: dependence and tolerance are major restricting factors in the clinical use of opioid analgesics. in the present study, the effects of thymoquinone, the major constituent of nigella sativa seeds, on morphine dependence and tolerance were investigated in mice. materials and methods: male adult nmri mice were made tolerant and dependent by repeated injections of morphine (50, 50, and 7...

aim: the purpose of this study was to compare the attention bias about tempting incentives related to opium materials in treated, addicted and normal people. duration of consumption and treating were also considered. method: in this causal-comparative study population was all addicted people who were referred to the rehabilitation offices, addiction treatment clinic, rebirthing centers and narc...