BACKGROUND The prevalence of dermatophytosis in the general population is high, particularly in patients with chronic renal failure. Treatment requires the use of topical and/or systemic antifungal drugs. The efficacy of antifungal agents for the treatment of dermatophytosis has yet to be evaluated. Studies evaluating the in vitro activity of antifungal agents are rare, particularly in filament...

Introduction In recent years, the remarkable increase in the number of infections caused by fungal pathogens, especially in immunocompromised people, has stimulated interest in medical mycology in general and in antifungal susceptibility testing in particular. 1,2 In-vitro procedures for determining the activity of drugs against mould and yeast isolates involve clinicians in the choice and moni...

The treatment of vulvovaginal candidiasis (VVC) due to Candida glabrata is challenging, with limited therapeutic options. Unexplained disappointing clinical efficacy has been reported with systemic and topical azole antifungal agents in spite of in vitro susceptibility. Given that the vaginal pH of patients with VVC is unchanged at 4 to 4.5, we studied the effect of pH on the in vitro activity ...

Background Candida species are normal microflora of  oral cavity, vagina, and gastrointestinal  tract. They are the third most prevalent cause of pediatric health care–associated  bloodstream fungal infection. This study aimed to provide an epidemiological feature of candidiasis and also presents an antifungal susceptibility profile of clinical Candida iso...

The prevalence of drug resistance has become an important issue in various yeast infections, which have a significant effects on both human animal health. In this study, an attempt has been made to determine susceptibility pattern of two antifungal agents Terbinafine and Ketoconazole against 45 oral and non oral Candida albicans isolates using broth microdilution method. Under in vitro conditio...