نتایج جستجو برای: in silico

تعداد نتایج: 16976349  

The properties relevant to pharmacokinetics and pharmacodynamics of four series of synthesized s-triazine derivatives have been studied by Quantitative structure-retention relationship (QSRR) approach. The chromatographic behavior of these compounds was investigated by using reversed-phase high performance thin-layer chromatography (RP-HPTLC). Chromatographic retention (RM0) was correlated with...

Journal: :Critical Care Medicine 2013

Journal: :Nature Biotechnology 2008

Journal: :acta medica iranica 0
masoumeh mohebi farabi eye research center, farabi eye hospital, tehran university of medical sciences, tehran, iran. abolfazl akbari colorectal research center, iran university of medical sciences, tehran, iran. nahid babaei department of molecular cell biology and genetics, bushehr branch, islamic azad university, bushehr, iran. abdolrahim sadeghi department of biochemistry and genetics, molecular and medicine research center, arak university of medical sciences, arak, iran. mansour heidari department of molecular cell biology and genetics, bushehr branch, islamic azad university, bushehr, iran. and experimental medicine research center, tehran university of medical sciences, tehran, iran. and department of medical genetics, school of medicine, tehran university of medical sciences, tehran, iran.

autosomal dominant congenital cataract (adcc) is the most common form of inherited cataracts and accounts for one-third of congenital cataracts. heterozygous null mutations in the crystallin genes are the major cause of the adcc. this study aims to detect the mutational spectrum of four crystallin genes, cryba1/a3 , crybb1 , crybb2 and crygd in an iranian family. genomic dna was isolated from w...

Journal: :iranian journal of pharmaceutical research 0
baharak khoshkholgh-sima department of biology, science and research branch, islamic azad university, tehran, iran soroush sardari drug design and bioinformatics unit, medical biotechnology department, biotechnology research center, pasteur institute, #69, pasteur ave., tehran, 13164, iran. jalal izadi mobarakeh physiology and pharmacology department, pasteur institute of iran, #69, pasteur ave., tehran, 13164, iran ramezan ali khavari-nejad department of biology, science and research branch, islamic azad university, tehran, iran.

mycobacterium tuberculosis, the main cause of tuberculosis (tb), has still remained a global health crisis especially in developing countries. tuberculosis treatment is a laborious and lengthy process with high risk of non compliance, cytotoxicity adverse events and drug resistance in patient. recently, there has been an alarming rise of drug resistant in tb. in this regard, it is an unmet need...

Journal: :Nature Biotechnology 1999

Journal: :Journal of Chemical Theory and Computation 2021

Many important processes affecting the earth’s climate are determined by physical properties of seawater. In addition, desalination seawater is a significant source drinking water for human population living in coastal areas. Since governing these depend on molecular interactions among its components, deeper knowledge at level would contribute to better understanding phenomena. However, strong ...

Background and purpose: Different genera of enterobacteriaceae have important roles in gastrointestinal diseases such as diarrhea. Among these, Enterotoxigenic E. coli (ETEC), enterohemorrhagic E. coli (EHEC), and Shigella are three main bacteria which are transmitted via contaminated food and water. Vaccination is a good strategy to combat these pathogens. In the present study, a chimeric anti...

Journal: :Genome Biology 2001

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شاهد - دانشکده علوم پایه 1392

baumannii acinetobacter یک پاتوژن بیمارستانی با قدرت بیماری زایی در حال رشد است. این باکتری عفونت-های مقاوم به چندین آنتی بیوتیک ایجاد می کند و به درمان های دارویی و مواد ضد میکروبی به شدت مقاوم است. به همین علت نیاز روز افزونی به توسعه روش های جدید درمان بر علیه این پاتوژن نیاز است. سیستم های اکتساب آهن فاکتور های مهم ویرولانس این باکتری پاتوژن هستند. آنتی بادی بر علیه پروتئین های غشایی تحت تن...

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